5-fluoropyrimidine

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
BACKGROUND Antiangiogenic therapy has become the most important treatment modality for patients with advanced hepatocellular… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • figure 1
Is this relevant?
2007
2007
Enzymatic synthesis methods for the fluorinated 5'-triphosphate analogues 5F-UTP and 5F-CTP have been developed to facilitate 19F… (More)
Is this relevant?
2004
2004
Dihydropyrimidine dehydrogenase (DPD) is the rate-limiting enzyme of 5-fluoropyrimidine (5-FU) catabolism. We examined whether… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
Is this relevant?
1994
1994
Previous studies have shown that 100 nM 5-fluoroorotate (5-FO) is sufficient to block the in vitro proliferation of Plasmodium… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 2
  • table 1
Is this relevant?
1993
1993
Enzyme inhibition studies on extracts from human liver, mouse liver, and human placenta indicate that there are considerable… (More)
Is this relevant?
1993
1993
Prior studies from these laboratories demonstrated 3.2-fold potentiation of 5-fluorouracil (FUra) cytotoxicity by recombinant… (More)
Is this relevant?
1992
1992
5-Fluoroorotate is known to have potent antimalarial activity against chloroquine-susceptible as well as chloroquine-resistant… (More)
Is this relevant?
1992
1992
Structural changes in the macromolecular targets of pharmacological agents can result in alterations in the efficacy of these… (More)
Is this relevant?
1991
1991
Recombinant human interferon-alpha 2a (rIFN-alpha 2a; 500 or 5,000 IU/mL) or [6RS] leucovorin ([6RS]LV; 1 microM) each… (More)
Is this relevant?
1980
1980
The mouse T-lymphoma (S-49) cell line is useful for individually studying RNA- and DNA-directed effects of 5-fluoropyrimidines… (More)
  • table 1
  • table 2
Is this relevant?