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5-chlorouracil

 
National Institutes of Health

Papers overview

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2014
2014
We report on the shape resonance spectra of uracil, 5-fluorouracil, and 5-chlorouracil, as obtained from fixed-nuclei elastic… Expand
Highly Cited
2012
Highly Cited
2012
35/37Cl NMR spectroscopy studies of organic systems are very rare, with only a few neat liquids having been studied.1 The lack of… Expand
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Highly Cited
2006
Highly Cited
2006
Somatic mutations induced by oxidative damage of DNA might play important roles in atherogenesis. However, the underlying… Expand
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Highly Cited
2003
Highly Cited
2003
Oxidative damage to DNA has been implicated in carcinogenesis during chronic inflammation. Epidemiological and biochemical… Expand
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2003
2003
Hypochlorous acid (HOCl), generated from H2O2 and Cl– by myeloperoxidase in activated neutrophils, causes tissue damage during… Expand
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2001
2001
Recently, we have reported that tegafur, an anticancer agent, is biotransformed into active drug 5-fluorouracil (5-FU) by… Expand
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Review
1993
Review
1993
  • S. Morris
  • Mutation research
  • 1993
  • Corpus ID: 6702027
The halogenated pyrimidines were synthesized in the 1950s as potential anti-tumor agents after the discovery that certain tumors… Expand
Highly Cited
1992
Highly Cited
1992
In order to study the structure-activity relationships of dioxolane nucleosides as potential anti-HIV agents, various… Expand
Highly Cited
1988
Highly Cited
1988
The pharmacokinetics of 5-fluorouracil (5-FUra) was investigated in 21 patients with advanced cancer (mainly colorectal cancer… Expand
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Highly Cited
1957
Highly Cited
1957
A variety of structural analogues of purines and pyrimidines are known to affect the growth of viruses, bacteria and other micro… Expand
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