5-alpha-Dihydroprogesterone

Known as: 5-alpha-Pregnane-3,20-dione, 5 alpha Pregnanedione, 5alpha-Pregnane-3,20-dione 
A biologically active 5-alpha-reduced metabolite of plasma PROGESTERONE. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2009
02419752009

Papers overview

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Highly Cited
2006
Highly Cited
2006
BACKGROUND Alterations in the gamma-amino-butyric acid (GABA) neurotransmitter system have been identified in some populations… (More)
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2005
2005
A crucial biochemical reaction in vertebrates is progesterone conversion into neuroactive metabolites such as dihydroprogesterone… (More)
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Highly Cited
2003
Highly Cited
2003
We have previously shown that progesterone (PROG) is synthesized by Schwann cells and promotes myelin formation in the peripheral… (More)
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Highly Cited
2001
Highly Cited
2001
Allopregnanolone (ALLO), is a brain endogenous neurosteroid that binds with high affinity to gamma-aminobutyric acid type A (GABA… (More)
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2000
2000
Allopregnanolone (ALLO), a potent positive-allosteric modulator of the action of GABA at GABA(A) receptors, is synthesized in the… (More)
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2000
2000
We studied the effect of brain and spinal cord injury induced by fluid-percussion on the local synthesis of neurosteroids as… (More)
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1999
1999
The aims of the present study were to (i) determine the relative abundance of the 5alpha-reduced progestins 5alpha-pregnane-3-ol… (More)
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1998
1998
A number of A-ring-reduced metabolites of deoxycorticosterone and progesterone, known to exert agonist activity at the GABA(A… (More)
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Highly Cited
1997
Highly Cited
1997
Post-mortem concentrations of progesterone, 5alpha-pregnane-3,20-dione (5alpha-DHP) and 3alpha-hydroxy-5alpha-pregnane-20-one… (More)
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1997
1997
5Alpha-dihydroprogesterone (5alpha-DHP) is the immediate precursor of 5alpha-pregnan-3alpha-ol-20-one, a potent anxiolytic… (More)
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