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5-HT>3< receptor antagonist

Known as: 5-hydroxytryptamine 3 receptor antagonist, 5 ht3 antagonists receptor, 5-ht3 receptor antagonist 
Any agent that binds to and blocks serotonin (5-HT) type 3 receptors. This group of agents is used to treat nausea, vomiting, and irritable bowel… 
National Institutes of Health

Related topics

Related topics

3 relations
Serotonin 3 Receptor Antagonists [MoA]Serotonin-3 Receptor Antagonist [EPC]

Broader (1)

Serotonin 5-HT3 Receptor Antagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Sleep Deprivation-Induced Blood-Brain Barrier Breakdown and Brain Dysfunction are Exacerbated by Size-Related Exposure to Ag and Cu Nanoparticles. Neuroprotective Effects of a 5-HT3 Receptor…
Military personnel are often subjected to sleep deprivation (SD) during combat operations. Since SD is a severe stress and alters… 
2015
2015
A 5-HT3 receptor antagonist potentiates the behavioral, neurochemical and electrophysiological actions of an SSRI antidepressant
Review
2015
Review
2015
Efficacy of palonosetron for preventing postoperative nausea and vomiting: a systematic review and meta-analysis
PurposePalonosetron, a second-generation 5-hydroxytryptamine 3 receptor antagonist (5-HT3RA), has unique characteristics relative… 
Review
2014
Review
2014
Efficacy and safety of palonosetron for the prophylaxis of chemotherapy-induced nausea and vomiting (CINV): a systematic review and meta-analysis of randomized controlled trials
PurposePalonosetron, a 5-hydroxytryptamine 3 receptor antagonist (5-HT3RA) with a strong binding affinity and long half-life, has… 
Review
2009
Review
2009
Palonosetron: a second generation 5-hydroxytryptamine 3 receptor antagonist
Background: Chemotherapy-induced nausea and vomiting (CINV) is associated with a significant deterioration in quality of life… 
1999
1999
The alpha9 nicotinic acetylcholine receptor shares pharmacological properties with type A gamma-aminobutyric acid, glycine, and type 3 serotonin receptors.
In the present study, we provide evidence that the alpha9 nicotinic acetylcholine receptor (nAChR) shares pharmacological… 
1996
1996
Effect of nonpeptide motilin agonist EM523 on release of gut and pancreatic hormones in conscious dogs.
BACKGROUND & AIMS EM523, a nonpeptide motilin agonist, is being developed for clinical use to improve delayed gastric emptying… 
1995
1995
Serotonergic modulation of cat bladder function before and after spinal transection.
Highly Cited
1991
Highly Cited
1991
MDL72222, a serotonin 5-HT3 receptor antagonist, blocks MDMA's ability to establish a conditioned place preference
Highly Cited
1988
Highly Cited
1988
Reversal of the antinociceptive effects of intrathecally administered serotonin in the rat by a selective 5-HT3 receptor antagonist
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