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5,12-diHETE

Known as: 5,12 HETE, 5,12 diHETE, 5,12-HETE 
National Institutes of Health

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Leukotriene B4

Papers overview

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2003
2003
Platelets may inhibit leucotriene biosynthesis by human neutrophils at the integrin level
Summary. Polymorphonuclear leucocytes and blood platelets co‐operate in several pathophysiological processes, and arachidonic… 
1999
1999
Platelet Contribution to Leukotriene Production in Inflammation: In Vivo Evidence in the Rabbit
Summary The contribution of platelets to arachidonic acid transcellular metabolism may represent an important pathway of… 
1993
1993
Identification of 5-keto-(7E,9E,11Z,14Z)-eicosatetraenoic acid as a novel nonenzymatic rearrangement product of leukotriene A4.
Leukotriene A4 (LTA4), the reaction product of 5-lipoxygenase in human polymorphonuclear (PMN) leukocytes, is transformed both to… 
1991
1991
Regional distribution of lipoxygenase activities in porcine ciliary epithelium.
Nonpigmented epithelial (NPE) cells and pigmented epithelial (PE) cells were separated from porcine ciliary processes without… 
1990
1990
Interaction of 5-HETE, 12-HETE, 15-HETE and 5,12-diHETE at the human platelet thromboxane A2/prostaglandin H2 receptor.
A variety of lipoxygenase products such as 12- and 15-hydroxyeicosatetraenoic acid (12- and 15-HETE) inhibit thromboxane A2 (TXA2… 
1986
1986
Ionophore-dependent generation of eicosanoids in human dispersed lung cells. Modulation by 6,9-deepoxy-6,9-(phenylimino)-delta 6,8-prostaglandin I1 (U-60,257).
1985
1985
Increased activity of 5-lipoxygenase in polymorphonuclear leukocytes from asthmatic patients.
1983
1983
Synthesis and 5-lipoxygenase inhibitory activities of eicosanoid compounds.
Ten eicosanoid compounds (3, 6, 9, 11, 12, 15, 18, 21, 23, and 25), methyl (6E,8Z,11Z,14Z)-5-hydroxy-6,8,11,14-eicosatetraenoate… 
1981
1981
Metabolic requirements for rabbit polymorphonuclear leucocyte lipoxygenase activity.
Lipoxygenase product formation by rabbit PMNs on exposure to the divalent ionophore A23187 was dependent upon pH, metabolic… 
Highly Cited
1980
Highly Cited
1980
Fatty acid structural requirements for leukotriene biosynthesis.
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