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4-nitroimidazole

Known as: 5-nitroimidazole 
National Institutes of Health

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Nitroimidazoles

Papers overview

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Review
2014
Review
2014
[The current view of the diagnosis and management of amebiasis in the light of the authors own case reports].
This comprehensive review is focused on a serious protozoan disease, amebiasis. This disease is caused by the human parasite… 
2011
2011
Effect of polymers and excipients on the release kinetics, bioadhesion, and floatability of metronidazole tablet
Stomach-specific floating tablet of metronidazole based on the buoyancy and bioadhesion concept was prepared with a purpose to… 
2003
2003
Hydrolysis of tinidazole : Analytical methods and degradation kinetics
Tinidazole, chemically 1-[2-(ethylsulfonyl)ethyl]−2-methyl−5-nitroimidazole, as well as metronidazole and ornidazole, are 5… 
1986
1986
Studies on the mechanism of activation and the mutagenicity of ronidazole, a 5-nitroimidazole.
Substantial evidence implicates the obligatory nucleophilic attack by water at C4 for the elimination of the carbamate and… 
Review
1981
Review
1981
Therapeutic efficacy of several nitroimidazoles for experimental Trypanosoma cruzi infections in mice.
Several, substituted 5-nitroimidazole analogs were compared for efficacy against experimen- tal Trypanosoma cruzi infections in… 
1981
1981
New chemotherapeutic nitroheterocycles active against 5-nitroimidazole-resistant strains of trichomonads.
The synthesis and the trichomonacidal activity of some 4-substituted 2-imidazolylquinazoline derivatives are described. The new… 
1979
1979
Comparison of the genetic activity of 5-nitroimidazole derivatives in Escherichia coli, Neurospora crassa, Saccharomyces cerevisiae and Drosophila melanogaster.
5-nitroimidazoles, including metronidazole (compound 1) and 3 analogues (compounds 2, 3 and 4) of actual or potential… 
1978
1978
Comparative study of SQ 18 506 with other nitroheterocyclic compounds on experimental Chagas' disease.
The activity of the 5-nitrovinylfuran, SQ 18 506, is compared in vivo and in vitro with lampit (a 5-nitrofuran), Ro 7-1051 (a 2… 
1975
1975
Electron-affinic sensitization. VI. A pulse radiolysis and ESR comparison of some 2- and 5-nitroimidazoles.
1970
1970
Absorptiometric, polarographic, and gas chromatographic assays for the determination of N-1-substituted nitroimidazoles in blood and urine.
This report describes an absorptiometric, a polarographic, and a gas-liquid chromatographic assay procedure for the quantitative…