4-hydroxytriazolam
National Institutes of Health
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The objective of this study was to examine urinary excretion profiles of two major triazolam metabolites, alpha-hydroxytriazolam…
In human liver microsomes, triazolam is principally metabolized by CYP3A4 to form two metabolites, 1'-hydroxytriazolam (1'OHTz…
Rifabutin is effective in the treatment and prevention of Mycobacterium avium infection in people with HIV infection. Rifabutin…
A sensitive method using reversed-phase liquid chromatography coupled with electrospray ionization mass spectrometry has been…
Phenyldiazene reacted with lymphoblast-expressed CYP3A4 to give a stable phenyl-iron complex that could be induced to rearrange…
We previously demonstrated that ketoconazole is a potent inhibitor of triazolam biotransformation in vitro and in vivo. Despite…