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Determination of salvinorin A and salvinorin B in Salvia divinorum-related products circulated in Japan.
Two major salvinorins, salvinorin A (SalA) and salvinorin B (SalB), in three Salvia divinorum dried leaf products and nine of its "concentrated extract" products circulated in Japan were determined.Expand
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Determination of muscimol and ibotenic acid in Amanita mushrooms by high-performance liquid chromatography and liquid chromatography-tandem mass spectrometry.
A reliable analytical method was developed for the quantification and identification of muscimol (MUS) and ibotenic acid (IBO), the toxic constituents of Amanita muscaria and Amanita pantherina. MUSExpand
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Detection of main metabolites of XLR-11 and its thermal degradation product in human hepatoma HepaRG cells and human urine.
The metabolism of (1-(5-fluoropentyl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone (XLR-11), a novel synthetic cannabinoid, was studied using a HepaRG cell culture. The HepaRG cells wereExpand
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Time-course measurements of caffeine and its metabolites extracted from fingertips after coffee intake: a preliminary study for the detection of drugs from fingerprints
The aim of this study was to determine whether an ingested drug and its metabolites could be detected in the subject’s fingerprints. Caffeine (CF) was chosen as the model drug. Three healthy subjectsExpand
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In vitro stability and metabolism of salvinorin A in rat plasma
Salvinorin A is the main active psychoactive ingredient in Salvia divinorum, a Mexican plant that has been widely available as a hallucinogen in recent years. The aims of this study were toExpand
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Uptake of 3,4-methylenedioxymethamphetamine and its related compounds by a proton-coupled transport system in Caco-2 cells.
3,4-methylenedioxymethamphetamine (MDMA) is an illegal amphetamine-type stimulant (ATS) that is abused orally in the form of tablets for recreational purposes. The aim of this work is to investigateExpand
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Profiling of seized methamphetamine putatively synthesized by reductive amination of 1-phenyl-2-propanone
We report a case of seized methamphetamine (MA) samples showing unique drug profiles. Conventional drug profiling such as impurity profiling and chiral analysis as well as stable isotope ratio massExpand
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Degradation pathways of 4-methylmethcathinone in alkaline solution and stability of methcathinone analogs in various pH solutions.
Analogs of methcathinone (MC), a psychoactive stimulant, are in circulation all over the world. These analogs have been assumed to be unstable in alkaline solutions, as is MC itself. The aims of thisExpand
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A method for screening for various sedative-hypnotics in serum by liquid chromatography/single quadrupole mass spectrometry.
A screening method for the detection of sedative-hypnotics in serum is described. The target drugs, which include practically all the sedative-hypnotics distributed in Japan, consisted of 5Expand
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Comparison and classification of methamphetamine seized in Japan and Thailand using gas chromatography with liquid-liquid extraction and solid-phase microextraction.
Methamphetamine (MA) is one of the most frequently abused drugs worldwide. The aim of this study is to improve the analytical method for profiling MA impurity in order to compare and classify MAExpand
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