4-anilidopiperidine
National Institutes of Health
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Enkephalin analogues with a 4-anilidopiperidine scaffold have been designed and synthesized to achieve therapeutic benefit for…
Remifentanil (Ultiva™), a 4-anilidopiperidine derivative of fentanyl, is an ultrashort-acting μ-opioid receptor agonist indicated…
Remifentanil is the latest available compound of the 4-anilidopiperidine derivatives. It is characterized by an ultrashort…
Remifentanil is a 4-anilidopiperidine mu-opioid analgesic which is rapidly metabolized by unspecific blood and tissue esterases…
Synthesis, analgesic activity and preliminary molecular modeling studies of the cisand trans-fused octahydro-l,2,3,4,4a,5,11,1 la…
Fentanyl, and its structural analogs lofentanil and sufentanil, are potent analgesics used clinically in the management of pain…
Current trends toward outpatient surgery and closed loop computer controlled drug administration have created a demand for short…
A simple mathematical model of analgesia in the rat is developed and utilized to determine quantitative structure-activity…