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4-amino-5-hexynoic acid

Known as: 4-aminohex-5-ynoic acid, gamma-acetylenic GABA, gamma-acetylenic-GABA 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

6-Aminocaproic AcidAlkynesAminocaproatesEnzyme Inhibitors

Narrower (1)

RMI 71645

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Design and Mechanism of GABA Aminotransferase Inactivators. Treatments for Epilepsies and Addictions.
When the brain concentration of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) diminishes below a threshold level… 
2014
2014
Amidation reactions from the direct coupling of metal carboxylate salts with amines.
A general method for the synthesis of amides involving the direct coupling of alkali metal carboxylate salts with amines is… 
Highly Cited
2011
Highly Cited
2011
Ultra-fast rotors for molecular machines and functional materials via halogen bonding: crystals of 1,4-bis(iodoethynyl)bicyclo[2.2.2]octane with distinct gigahertz rotation at two sites.
As a point of entry to investigate the potential of halogen-bonding interactions in the construction of functional materials and… 
Highly Cited
2011
Highly Cited
2011
Characterization of vinylgold intermediates: gold-mediated cyclization of acetylenic amides.
Vinylgold intermediates involved in various gold-catalyzedreactions are known to undergo proto-deauration in thepresence of a… 
Highly Cited
2010
Highly Cited
2010
QSAR modeling of toxicity of diverse organic chemicals to Daphnia magna using 2D and 3D descriptors.
Highly Cited
2010
Highly Cited
2010
Amplification of chirality in monodisperse, enantiopure alleno-acetylenic oligomers.
2009
2009
An unexpected rearrangement that disassembles alkyne moiety through formal nitrogen atom insertion between two acetylenic carbons and related cascade transformations: new approach to Sampangine…
This work analyzes multiple new reaction pathways which originate from intramolecular reactions of activated alkynes with the… 
Highly Cited
2002
Highly Cited
2002
Synthesis of C-carbamoyl-1,2,3-triazoles by microwave-induced 1,3-dipolar cycloaddition of organic azides to acetylenic amides.
1,3-Dipolar cycloaddition of organic azides 1, 2, or 3 to acetylenic amides 4 or 5 under solvent-free microwave irradiation… 
2001
2001
A simple and efficient approach for the synthesis of fluorinated and nonfluorinated octaethylporphyrin-based benzochlorins with variable lipophilicity, their in vivo tumor uptake, and the preliminary…
Starting from commercially available Ni(II)octaethylporphyrin (OEP), an efficient approach for the preparation of a series of… 
Highly Cited
1998
Highly Cited
1998
Acetylenic Cyclophanes as Fullerene Precursors: Formation of C60 H6 and C60 by Laser Desorption Mass Spectrometry of C60 H6 (CO)12.
A logical precursor of macrocycle C60 H6 , cyclophane C60 H6 (CO)12 (1) represents a building block in a possible total synthesis… 
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