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3,15,17-trihydroxypregnan-20-one

Known as: 3 alpha,15 beta,17 alpha-trihydroxy-5 beta-pregnan-20-one, 3,15,17-TH-5P, 3,15,17-trihydoxy-5alpha-pregnan-20-one 
National Institutes of Health

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2 relations

Broader (1)

Pregnanetriol
analogs & derivatives

Papers overview

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2006
2006
Neurosteroid modulation of recombinant rat alpha5beta2gamma2L and alpha1beta2gamma2L GABA(A) receptors in Xenopus oocyte.
GABA(A) receptors containing alpha(5)-subunit have an important role in cognitive function. As the agonistic effect of 3alpha… 
2005
2005
Evaluation of O(3alpha)-, O(21)-di-(N(1)-methyloxycarbonyl-2, 4-dioxo-5-fluoropyrimidinyl) 17alpha-hydroxy-5beta-pregnan-20-one as a novel potential antiangiogenic codrug.
Intraocular neovascularization is a complication in a variety of eye diseases, and is a leading cause of visual loss. The purpose… 
2003
2003
A New Pregnane Derivative from the Indian Ocean Gorgonian Subergorgia suberosa (Pallas)
3, 3-Dimethoxy-5a-pregnan-20-one 1, a new compound, has been isolated from the gorgonian S. suberosa. 
1997
1997
Use of a radioimmunoassay which detects C21 steroids with a 5beta-reduced, 3alpha-hydroxylated configuration to identify and measure steroids involved in final oocyte maturation in female plaice…
Two radioimmunoassays (RIAs) have been developed which detect C21 (pregnane) steroids with a 5beta-reduced, 3alpha-hydroxyl… 
1997
1997
Partial agonism by 3alpha,21-dihydroxy-5beta-pregnan-20-one at the gamma-aminobutyric acidA receptor neurosteroid site.
3alpha,21-Dihydroxy-5alpha-pregnan-20-one (5alpha-THDOC) and 3alpha-hydroxy-5alpha-pregnan-20-one (3alpha,5alpha-P) have full… 
1993
1993
New identified 15β-hydroxylated 21-deoxy-pregnanes in congenital adrenal hyperplasia due to 21-hydroxylase deficiency
1980
1980
The early recognition of the 21-hydroxylase deficiency variety of congenital adrenal hyperplasia.
1977
1977
Steroids and related products. XLIII The synthesis of 17-hydroxymethylprogesterone
1973
1973
Female Pattern of Metabolism of [4-14C]Corticosterone in Male Pseudohermaphroditic Rats
Summary The metabolites of [4-14C]corticosterone appearing in bile fistulae of male pseudohermaphrodites and littermate male and… 
1961
1961
The Metabolism of 4-C14-Testosterone in Rat Testis Homogenate
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