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3'-methyl-4-methylaminoazobenzene

Known as: 3'-Me-MAB, 3'-methyl-4-MAB, 3'-methyl-N-methyl-4-aminoazobenzene 
 
National Institutes of Health

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3 relations
3-methyl-4-methylaminoazobenzeneanalogs & derivatives

Broader (1)

p-Dimethylaminoazobenzene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1984
1984
4-aminoazobenzene and N,N-dimethyl-4-aminoazobenzene as equipotent hepatic carcinogens in male C57BL/6 X C3H/He F1 mice and characterization of N-(Deoxyguanosin-8-yl)-4-aminoazobenzene as the major…
In contrast to the well-established requirement for an N-methyl group for efficient hepatic tumor induction by dietary… Expand
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1981
1981
A comparison of the carcinogen-DNA adducts formed in rat liver in vivo after administration of single or multiple doses of N-methyl-4-aminoazobenzene.
N-Methyl-4-aminoazobenzene (MAB) is believed to be metabolized in the liver to an electrophilic N-sulfonyloxy ester which binds… Expand
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1981
1981
DNA adducts formed from N-benzoyloxy-N-methyl-4-aminoazobenzene in vitro and from N, N-dimethyl-4-aminoazobenzene in mouse liver.
Reaction of N-benzoyloxy-N-methyl-4-aminoazobenzene with (14C) deoxyguanosine yielded a series of at least 10 dye derivatives… Expand
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1980
1980
Estimation of apurinic/apyrimidinic sites and phosphotriesters in deoxyribonucleic acid treated with electrophilic carcinogens and mutagens.
The number of apurinic/apyrimidinic (AP) sites in supercoiled SV40 deoxyribonucleic acid (DNA) after treatment with several… Expand
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1980
1980
Adducts from the reaction of N-benzoyloxy-N-methyl-4-aminoazobenzene with deoxyguanosine or DNA in vitro and from hepatic DNA of mice treated with N-methyl- or N,N-dimethyl-4-aminoazobenzene.
N-Benzoyloxy-N-methyl-4-aminoazobenzene, a synthetic model ultimate carcinogenic derivative of N-methyl- and N,N-dimethyl-4… Expand
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  • table 2
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1976
1976
Microsomal N-oxidation of the hepatocarcinogen N-methyl-4-aminoazobenzene and the reactivity of N-hydroxy-N-methyl-4-aminoazobenzene.
The N-oxidation of the hepatocarcinogen N-methyl-4-aminoazobenzene (MAB) was catalyzed by hepatic microsomes in a reduced… Expand
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  • table 5
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Review
1976
Review
1976
Hepatic metabolism of N-hydroxy-N-methyl-4-aminoazobenzene and other N-hydroxy arylamines to reactive sulfuric acid esters.
Hepatic cytosols catalyzed a 3'-phosphoadenosine 5'-phosphosulfate (PAPS)-dependent O-sulfonation of N-hydroxy-N-methyl-4… Expand
  • table 1
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  • table 3
  • table 5
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1976
1976
Studies on carcinogenic azo dyes. VII. Changes in the hepatic activities of 3'-Me-DAB metabolism by rat, mouse, and hamster during the repeated administration of 3'-Me-DAB.
The metabolic pattern of 3'-methyl-4-dimethylaminoazobenzene (3'-Me-DAB) in the rat liver through the course of hepatic… Expand
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1975
1975
N-substitution of carbon 8 in guanosine and deoxyguanosine by the carcinogen N-benzoyloxy-N-methyl-4-aminoazobenzene in vitro.
The major reaction products of the carcinogenic electrophile N-benzoyloxy-N-methyl-4-aminoazobenzene with guanosine or… Expand
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1975
1975
Sfructures of Hepatic Nucleic Acid-boundDyes in Rats Given the Carcinogen 4'
Rats were given the hepatocarcinogenic dye N-methyl-4aminoazobenzene labeled in the prime ring with tritium. The hepatic… Expand
  • table I
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