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3',4'-dimethoxyflavone

Known as: 3',4'-DMF 
National Institutes of Health

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Broader (1)

Flavones

Papers overview

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2013
2013
Identification through high‐throughput screening of 4'‐methoxyflavone and 3',4'‐dimethoxyflavone as novel neuroprotective inhibitors of parthanatos
The current lack of disease‐modifying therapeutics to manage neurological and neurodegenerative conditions justifies the… Expand
2011
2011
Genotoxicity and apoptosis in Drosophila melanogaster exposed to benzene, toluene and xylene: attenuation by quercetin and curcumin.
Monocyclic aromatic hydrocarbons (MAHs) such as benzene, toluene and xylene are being extensively used for various industrial and… Expand
2009
2009
Involvement of oxidative stress and activation of aryl hydrocarbon receptor in elevation of CYP1A1 expression and activity in lung cells and tissues by arsenic: an in vitro and in vivo study.
Epidemiological evidence indicated that there was a synergistic interaction between arsenic and cigarette smoke on enhancement of… Expand
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2008
2008
Cytotoxic effects of the dietary flavones chrysin and apigenin in a normal trout liver cell line.
Many flavonoids have been shown to possess prooxidant properties, capable of causing oxidative stress, especially at larger doses… Expand
Highly Cited
2006
Highly Cited
2006
Methylation protects dietary flavonoids from rapid hepatic metabolism
  • X. Wen, T. Walle
  • Xenobiotica; the fate of foreign compounds in…
  • 2006
    • Corpus ID: 34973846
The metabolic stability of two potential cancer chemopreventive flavones, i.e. 5,7-dimethoxyflavone (5,7-DMF) and 3′,4… Expand
2006
2006
Inhibition of benzo[a]pyrene-activating enzymes and DNA binding in human bronchial epithelial BEAS-2B cells by methoxylated flavonoids.
Cigarette smoking is a major risk factor in lung carcinogenesis via carcinogens such as polycyclic aromatic hydrocarbons (PAHs… Expand
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Highly Cited
2005
Highly Cited
2005
Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity.
Metabolism of polycyclic aromatic hydrocarbons (PAHs) has been studied intensively, and potential metabolites with estrogenic… Expand
Highly Cited
2005
Highly Cited
2005
Preferential induction of CYP1B1 by benzo[a]pyrene in human oral epithelial cells: impact on DNA adduct formation and prevention by polyphenols.
The roles of CYP1A1 and 1B1 in tobacco smoke carcinogen, e.g. benzo[a]pyrene (BaP), induced DNA binding and their inhibition by… Expand
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Highly Cited
2005
Highly Cited
2005
Lipophilic flavones of Primula veris L. from field cultivation and in vitro cultures.
Ten lipophilic flavones were isolated from the leaves of Primula veris from field cultivation - the newly described 3'-hydroxy-4… Expand
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Highly Cited
2000
Highly Cited
2000
3',4'-dimethoxyflavone as an aryl hydrocarbon receptor antagonist in human breast cancer cells.
  • J. Lee, S. Safe
  • Toxicological sciences : an official journal of…
  • 2000
    • Corpus ID: 42313255
Treatment of MCF-7 and T47D human breast cancer cells with 3', 4'-dimethoxyflavone (3',4'-DMF) alone did not induce CYP1A1… Expand
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