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3',4'-dimethoxyflavone

Known as: 3',4'-DMF 
 
National Institutes of Health

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Broader (1)

Flavones

Papers overview

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2013
2013
Identification through high-throughput screening of 4'-methoxyflavone and 3',4'-dimethoxyflavone as novel neuroprotective inhibitors of parthanatos.
BACKGROUND AND PURPOSE The current lack of disease-modifying therapeutics to manage neurological and neurodegenerative conditions… Expand
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2011
2011
Genotoxicity and apoptosis in Drosophila melanogaster exposed to benzene, toluene and xylene: attenuation by quercetin and curcumin.
Monocyclic aromatic hydrocarbons (MAHs) such as benzene, toluene and xylene are being extensively used for various industrial and… Expand
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2009
2009
Involvement of oxidative stress and activation of aryl hydrocarbon receptor in elevation of CYP1A1 expression and activity in lung cells and tissues by arsenic: an in vitro and in vivo study.
Epidemiological evidence indicated that there was a synergistic interaction between arsenic and cigarette smoke on enhancement of… Expand
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2008
2008
Cytotoxic effects of the dietary flavones chrysin and apigenin in a normal trout liver cell line.
Many flavonoids have been shown to possess prooxidant properties, capable of causing oxidative stress, especially at larger doses… Expand
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2006
2006
Inhibition of benzo[a]pyrene-activating enzymes and DNA binding in human bronchial epithelial BEAS-2B cells by methoxylated flavonoids.
Cigarette smoking is a major risk factor in lung carcinogenesis via carcinogens such as polycyclic aromatic hydrocarbons (PAHs… Expand
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2006
2006
Methylation protects dietary flavonoids from rapid hepatic metabolism
The metabolic stability of two potential cancer chemopreventive flavones, i.e. 5,7-dimethoxyflavone (5,7-DMF) and 3′,4… Expand
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Highly Cited
2005
Highly Cited
2005
Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity.
Metabolism of polycyclic aromatic hydrocarbons (PAHs) has been studied intensively, and potential metabolites with estrogenic… Expand
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2005
2005
Preferential induction of CYP1B1 by benzo[a]pyrene in human oral epithelial cells: impact on DNA adduct formation and prevention by polyphenols.
The roles of CYP1A1 and 1B1 in tobacco smoke carcinogen, e.g. benzo[a]pyrene (BaP), induced DNA binding and their inhibition by… Expand
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2005
2005
Lipophilic flavones of Primula veris L. from field cultivation and in vitro cultures.
Ten lipophilic flavones were isolated from the leaves of Primula veris from field cultivation - the newly described 3'-hydroxy-4… Expand
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2000
2000
3',4'-dimethoxyflavone as an aryl hydrocarbon receptor antagonist in human breast cancer cells.
Treatment of MCF-7 and T47D human breast cancer cells with 3', 4'-dimethoxyflavone (3',4'-DMF) alone did not induce CYP1A1… Expand
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