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2-methyl-4-isothiazolin-3-one

Known as: Methylisothiazolinone, 2-Methyl-3(2H)-isothiazolone, 2-methyl-4-isothiazolin-3-one [Chemical/Ingredient] 
National Institutes of Health

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49 relations

Narrower (1)

2-methyl-4-isothiazolin-3-one hydrochloride
Aluminum Sesquichlorohydrate 0.17 g in 1 mL TOPICAL LIQUID [ESIKA AVENTOUR Roll-On]Benzalkonium Chloride 1 MG/ML Medicated Liquid Soap [Lysol No-Touch Hand Soap]Benzalkonium Chloride 1.15 MG/ML Medicated PadBenzalkonium Chloride 1.2 MG/ML Topical Solution

Broader (2)

Anti-Infective AgentsDisinfectants

Papers overview

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Highly Cited
2011
Highly Cited
2011
Contact sensitization to methylisothiazolinone in Finland—a multicentre study
Background. Antimicrobials constitute the second most common cause of contact allergy to cosmetics. Methylisothiazolinone (MI… 
2007
2007
Prediction of preservative sensitization potential using surface marker CD86 and/or CD54 expression on human cell line, THP-1
Preservatives are important components in many products, but have a history of purported allergy. Several assays [e.g., guinea… 
Highly Cited
2002
Highly Cited
2002
Elucidating changes in surface marker expression of dendritic cells following chemical allergen treatment.
Dendritic cells (DC) are highly specialized antigen-presenting cells (APC) located in lymphoid and many nonlymphoid tissues, and… 
Highly Cited
2002
Highly Cited
2002
Occupational relevance of positive standard patch-test results in employed persons with an initial report of an occupational skin disease
AbstractObjectives. It is commonly accepted that the standard screening tray is an essential diagnostic test in patch testing… 
Highly Cited
1999
Highly Cited
1999
Influence of application vehicle on skin sensitization to methylchloroisothiazolinone/methylisothiazolinone: an analysis using the local lymph node assay
The murine local lymph node assay (LLNA) is a method for the identification of skin sensitizing chemicals in which activity is… 
Review
1998
Review
1998
Occupational dermatoses in a plant producing binders for paints and glues
A survey of occupational dermatoses, based on a questionnaire, clinical examination and patch testing, was carried out among… 
Highly Cited
1995
Highly Cited
1995
The guinea pig maximization test--with a multiple dose design.
The guinea pig maximization test (GPMT) is usually performed with one moderately irritant induction dose of the allergen and… 
1991
1991
Relationship between use test and threshold patch test concentration in patients sensitive to 5‐chloro‐2‐methyl‐4‐isothiazolin‐3‐one and 2‐methyl‐4‐isothiazolin‐3‐one (MCI/MI)
A use test, formalized as a repeated open application test (ROAT) (1), is one way of evaluating the clinical relevance of a… 
Highly Cited
1989
Highly Cited
1989
ISOTHIAZOLINONE PRESERVATIVE: CAUSE OF A CONTINUING EPIDEMIC OF COSMETIC DERMATITIS
1986
1986
Allergic contact dermatitis due to a biocide containing 5‐chloro‐2‐methyl‐4‐isothiazohn‐3‐one
3 cases of contact allergy due to the biocides 5‐chloro‐2‐methyl‐4‐isothiazolin‐3‐one and 2‐methyl‐4‐isothiazolin‐3‐one are… 
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