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2-mercaptoethylguanidine

Known as: MEG-2SH, mercaptoethylguanidine 
 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
OBJECTIVES The aim of this study was to test whether peroxynitrite neutralizers would reduce peroxynitrite accumulation and… Expand
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Highly Cited
2001
Highly Cited
2001
Patients with severe burn and/or smoke inhalation injury suffer both systemic and pulmonary vascular hyperpermeability. We… Expand
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2000
2000
BACKGROUND In previous studies of transgenic sickle cell mice, increased renal expression of inducible nitric oxide synthase… Expand
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Highly Cited
1998
Highly Cited
1998
1. Excessive production of nitric oxide (NO), and the generation of peroxynitrite have been implicated in various proinflammatory… Expand
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Highly Cited
1998
Highly Cited
1998
In vitro studies have demonstrated that mercaptoethylguanidine (MEG), a selective inhibitor of the inducible NO synthase (iNOS… Expand
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1998
1998
Peroxynitrite (a potent oxidant produced by nitric oxide and superoxide) and hydroxyl radical, reactive oxidants produced during… Expand
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1998
1998
OBJECTIVE We recently identified mercaptoethylguanidine (MEG) as an antiinflammatory agent with a combined mechanism of action… Expand
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1998
1998
The effect of mercaptoethylguanidine (MEG), a selective inhibitor of the inducible nitric oxide synthase and peroxynitrite… Expand
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Highly Cited
1997
Highly Cited
1997
Nitric oxide (NO) produced by the inducible nitric-oxide synthase (iNOS) is responsible for some of the pathophysiological… Expand
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1997
1997
The effects of mercaptoethylguanidine, a dual inhibitor of the inducible nitric oxide (NO) synthase and cyclooxygenase with… Expand
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