2-mercaptoethylguanidine

OBJECTIVES The aim of this study was to test whether peroxynitrite neutralizers would reduce peroxynitrite accumulation and… Expand

Patients with severe burn and/or smoke inhalation injury suffer both systemic and pulmonary vascular hyperpermeability. We… Expand

BACKGROUND In previous studies of transgenic sickle cell mice, increased renal expression of inducible nitric oxide synthase… Expand

1. Excessive production of nitric oxide (NO), and the generation of peroxynitrite have been implicated in various proinflammatory… Expand

In vitro studies have demonstrated that mercaptoethylguanidine (MEG), a selective inhibitor of the inducible NO synthase (iNOS… Expand

Peroxynitrite (a potent oxidant produced by nitric oxide and superoxide) and hydroxyl radical, reactive oxidants produced during… Expand

OBJECTIVE We recently identified mercaptoethylguanidine (MEG) as an antiinflammatory agent with a combined mechanism of action… Expand

The effect of mercaptoethylguanidine (MEG), a selective inhibitor of the inducible nitric oxide synthase and peroxynitrite… Expand

Nitric oxide (NO) produced by the inducible nitric-oxide synthase (iNOS) is responsible for some of the pathophysiological… Expand

The effects of mercaptoethylguanidine, a dual inhibitor of the inducible nitric oxide (NO) synthase and cyclooxygenase with… Expand