2-mercaptoethylguanidine

Introduction. Nitric oxide (NO) and peroxynitrite (OONO—) are implicated in the pathophysiology of renal ischemia/reperfusion (I… Expand

OBJECTIVES The aim of this study was to test whether peroxynitrite neutralizers would reduce peroxynitrite accumulation and… Expand

Objective—We investigated the role of inducible NO synthase (iNOS) in intimal thickening with exposure to cigarette smoke (CS… Expand

Patients with severe burn and/or smoke inhalation injury suffer both systemic and pulmonary vascular hyperpermeability. We… Expand

Excessive production of nitric oxide (NO), and the generation of peroxynitrite have been implicated in various proinflammatory… Expand

In vitro studies have demonstrated that mercaptoethylguanidine (MEG), a selective inhibitor of the inducible NO synthase (iNOS… Expand

The effect of mercaptoethylguanidine (MEG), a selective inhibitor of the inducible nitric oxide synthase and peroxynitrite… Expand

ABSTRACT Peroxynitrite (a potent oxidant produced by nitric oxide and superoxide) and hydroxyl radical, reactive oxidants… Expand

OBJECTIVE We recently identified mercaptoethylguanidine (MEG) as an antiinflammatory agent with a combined mechanism of action… Expand

Nitric oxide (NO) produced by the inducible nitric-oxide synthase (iNOS) is responsible for some of the pathophysiological… Expand