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2-hydroxy-3-butynoate

Known as: alpha-hydroxybutynoate 
National Institutes of Health

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2-hydroxy-3-butynoic acid

Papers overview

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1996
1996
Purification and properties of glycolate oxidase from plants with different photosynthetic pathways: Distinctness of C4 enzyme from that of a C3 species and a C3–C4 intermediate
Glycolate oxidase (GO; EC 1.1.3.1) was purified from the leaves of three plant species:Amaranthus hypochondriacus L.(NAD-ME type… 
1985
1985
On the mechanism of flavin modification during inactivation of flavocytochrome b2 from baker's yeast by acetylenic substrates.
The reaction of 2-hydroxy-3-butynoate, a suicide substrate, with flavocytochrome b2 [F. Lederer (1974) Eur. J. Biochem. 88, 393… 
1983
1983
Evidence for the presence in tobacco leaves of multiple enzymes for the oxidation of glycolate and glyoxylate.
The enzymic oxidation of glycolate to glyoxylate and glyoxylate to oxalate by preparations purified from tobacco (Nicotiana… 
1982
1982
A residue critical for flavin binding in flavocytochrome b2 from Baker's yeast. Inactivation and labeling of flavin-free enzyme by 2-keto-3-butynoate.
The reagent 2-keto-3-butynoic acid is the product formed in the reaction between the suicide reagent 2-hydroxy-3-butynoate and a… 
1975
1975
Reversible inactivation of vectorial phosphorylation by hydroxybutynoate in Escherichia coli membrane vesicles.
The acetylenic hydroxy acid 2-hydroxy-3-butynoate causes irreversible inactivation of the Escherichia coli membrane-bound… 
Highly Cited
1974
Highly Cited
1974
On the first steps of lactate oxidation by bakers' yeast L-(plus)-lactate dehydrogenase (cytochrome b2).
The behaviour of bakers' yeast l-lactate dehydrogenase toward [2-2H]lactate 3-chlorolactate and 2-hydroxy-3-butynoate is reported… 
1973
1973
Reconstitution of D-lactate-dependent transport in membrane vesicles from a D-lactate dehydrogenase mutant of Escherichia coli.
Membrane-bound, flavin-linked D-lactate dehydrogenase in membrane vesicles of E. coli ML 308-225 is solubilized by extraction… 
1972
1972
Mechanisms of active transport in isolated bacterial membrane vesicles. X. Inactivation of D-lactate dehydrogenase and D-lactate dehydrogenase-coupled transport in Escherichia coli membrane vesicles…
Abstract The acetylenic hydroxy acid, 2-hydroxy-3-butynoate, is an irreversible inactivator of d-lactate dehydrogenase and d… 
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