2-aminoethoxydiphenyl borate

2-Aminoethoxydiphenyl borate (2-APB) has emerged as a useful pharmacological tool in the study of store-operated Ca(2+) entry… (More)

BACKGROUND AND PURPOSE Transient receptor potential melastatin 2 (TRPM2) is a non-selective Ca(2+)-permeable cation channel and… (More)

Stim1 in the endoplasmic reticulum and the three Orai (also termed CRACM) channels in the plasma-membrane are main components of… (More)

The emerging literature implicates a role for glia/cytokines in persistent pain. However, the mechanisms by which these non… (More)

1 2-aminoethoxydiphenyl borate (2-APB) has been widely used to examine the roles of inositol 1,4,5-trisphosphate receptors (IP3Rs… (More)

Six of the mammalian transient receptor potential (TRP) ion channel subtypes are nonselective cation channels that can be… (More)

The transient receptor potential (TRP) superfamily contains a large number of proteins encoding cation permeable channels that… (More)

The action of 2-aminoethoxydiphenyl borate (2-APB) on Ca(2+) signalling in HeLa cells and cardiac myocytes was investigated… (More)

Since its introduction to Ca2+ signaling in 1997, 2-aminoethoxydiphenyl borate (2-APB) has been used in many studies to probe for… (More)

The effects of a novel membrane-penetrable modulator, 2APB (2-aminoethoxy diphenyl borate), on Ins(1,4,5)P3-induced Ca2+ release… (More)