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2-aminoethoxydiphenyl borate

Known as: 2-APB compound, 2APB, bis phenyl(2-aminoethoxy)borate 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Boron Compounds

Papers overview

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Review
2013
Review
2013
The role of Ca2+ in the pathophysiology of pancreatitis
Acute pancreatitis is a human disease in which the pancreatic pro‐enzymes, packaged into the zymogen granules of acinar cells… 
Highly Cited
2008
Highly Cited
2008
2-Aminoethoxydiphenyl Borate Alters Selectivity of Orai3 Channels by Increasing Their Pore Size*
Stim1 in the endoplasmic reticulum and the three Orai (also termed CRACM) channels in the plasma-membrane are main components of… 
Highly Cited
2008
Highly Cited
2008
IP3 receptor-dependent Ca2+ release modulates excitation-contraction coupling in rabbit ventricular myocytes.
Inositol 1,4,5-trisphosphate (IP(3)) receptor (IP(3)R)-dependent Ca(2+) signaling exerts positive inotropic, but also… 
Highly Cited
2006
Highly Cited
2006
Block of Specific Gap Junction Channel Subtypes by 2-Aminoethoxydiphenyl Borate (2-APB)
2-Aminoethoxydiphenyl borate (2-APB), an inositol 1,4,5-triphosphate receptor modulator, inhibits capacitive current transients… 
Highly Cited
2004
Highly Cited
2004
Role of interstitial cells and gap junctions in the transmission of spontaneous Ca2+ signals in detrusor smooth muscles of the guinea‐pig urinary bladder
To investigate mechanisms underlying the transmission of spontaneous Ca2+ signals in the bladder, changes in intracellular… 
Highly Cited
2002
Highly Cited
2002
Modification of Store-operated Channel Coupling and Inositol Trisphosphate Receptor Function by 2-Aminoethoxydiphenyl Borate in DT40 Lymphocytes*
Store-operated channels (SOCs) provide an important means for mediating longer-term Ca2+ signals and replenishment of Ca2+stores… 
Highly Cited
2002
Highly Cited
2002
The role of inositol 1,4,5‐trisphosphate receptors in Ca2+ signalling and the generation of arrhythmias in rat atrial myocytes
Various cardio‐active stimuli, including endothelin‐1 (ET‐1), exhibit potent arrhythmogenicity, but the underlying cellular… 
Highly Cited
2001
Highly Cited
2001
2-Aminoethoxydiphenyl borate affects the inositol 1,4,5-trisphosphate receptor, the intracellular Ca2+ pump and the non-specific Ca2+ leak from the non-mitochondrial Ca2+ stores in permeabilized A7r5…
2-Aminoethoxydiphenyl borate (2APB) is a membrane-permeable blocker of the inositol 1,4,5-trisphosphate (IP3)-induced Ca2… 
Highly Cited
1999
Highly Cited
1999
The effects of 2-aminoethoxydiphenyl borate, a novel inositol 1,4, 5-trisphosphate receptor modulator on myometrial contractions.
These studies were performed to evaluate the effect of 2-aminoethoxydiphenyl borate (2-APB), a novel membrane-permeable inositol… 
Highly Cited
1979
Highly Cited
1979
Selective antagonism of amino acid‐induced and synaptic excitation in the cat spinal cord.
1. The effects of D‐alpha‐aminoadipate (DalphaAA), D‐alpha‐aminosuberate (DalphaAS) and other excitatory amino acid antagonists… 
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