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2'-cyano-2'-deoxyarabinofuranosylcytosine

Known as: 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine, 2'-cyano-2'deoxy-1-beta-D-arabinofuranosylcytosine, CNDAC 
National Institutes of Health

Papers overview

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2007
2007
This study assessed the antiproliferative activity of sapacitabine (CYC682, CS-682) in a panel of 10 human cancer cell lines with… Expand
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2005
2005
2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine (CNDAC) is a nucleoside analogue with a novel mechanism of action… Expand
Highly Cited
2004
Highly Cited
2004
Because membrane type‐1 matrix metalloproteinase (MT1‐MMP) is expressed specifically on the angiogenic endothelium as well as… Expand
Review
2004
Review
2004
Nucleoside analogues which show antimetabolic activity in cells have been successfully used in the treatment of various tumors… Expand
Highly Cited
2002
Highly Cited
2002
We previously reported that liposomalized 5′‐O‐dipalmitoylphosphatidyl 2′‐C‐cyano‐2′‐deoxy‐1‐β‐D‐arabino‐pentofuranosylcytosine… Expand
Highly Cited
2001
Highly Cited
2001
The mechanism of 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine (CNDAC) action was investigated in human… Expand
Highly Cited
1999
Highly Cited
1999
We have studied the antitumor activity and the novel DNA‐self‐strand‐breaking mechanism of CNDAC (1‐(2‐C‐cyano‐2‐deoxy‐β‐d… Expand
1995
1995
We have designed 2'-C-cyano-2'-deoxy-1-beta-D-arabino- pentofuranosylcytosine (CNDAC) as a potential mechanism-based DNA-strand… Expand
Highly Cited
1993
Highly Cited
1993
Design, synthesis, and tumor cell growth inhibitory effects of 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosyl derivatives of… Expand
Highly Cited
1992
Highly Cited
1992
The antitumor effects of 2'-C-cyano-2'-deoxy-1-beta-D- arabinofuranosylcytosine (CN-DAC), a synthetic 1-beta-D-arabinofuranosyl… Expand