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Photodynamic therapy targeted to tumor-induced angiogenic vessels.
Cancer photodynamic therapy (PDT) with benzoporphyrin derivative monoacid ring A (BPD-MA, verteporfin) may be effective not only by being directly cytotoxic to tumor cells, but also by beingExpand
Phthalate esters reveal skin-sensitizing activity of phenethyl isothiocyanate in mice.
Phenethyl isothiocyanate (PEITC) is a constituent of edible cruciferous vegetables and has received attention due to its potential cancer chemopreventive activity. Although its protein-bindingExpand
Intracellular target for photosensitization in cancer antiangiogenic photodynamic therapy mediated by polycation liposome.
Previous study indicated that antiangiogenic photodynamic therapy (PDT), laser irradiation at 15 min post-injection of photosensitizer in vivo, is effective for cancer treatment, and aExpand
Effects of phthalate esters on the sensitization phase of contact hypersensitivity induced by fluorescein isothiocyanate
Background Many different types of phthalate ester are used as plasticizers and are thus found in the air. There have been several studies that suggest an association between allergies and phthalateExpand
Antiangiogenic photodynamic therapy (PDT) using Visudyne causes effective suppression of tumor growth.
We previously observed that antiangiogenic photodynamic therapy (PDT), namely, laser irradiation at 15 min after administration of photosensitizer, by using stable liposomal benzoporphyrin derivativeExpand
Influence of Local Treatments with Capsaicin or Allyl Isothiocyanate in the Sensitization Phase of a Fluorescein-Isothiocyanate-Induced Contact Sensitivity Model
Background: In fluorescein isothiocyanate (FITC)-induced contact hypersensitivity models, dibutyl phthalate has been empirically used as a solvent ingredient. We have demonstrated that dibutylExpand
Restricted Expression of Shiga Toxin Binding Sites on Mucosal Epithelium of Mouse Distal Colon
ABSTRACT Shiga toxins (Stx) are some of the major virulence factors of enterohemorrhagic Escherichia coli strains such as serotype O157:H7. To explore how Stx might initially gain access to theExpand
Di-(2-ethylhexyl) phthalate enhances skin sensitization to isocyanate haptens in mice.
Toxicological and epidemiological studies have suggested the involvement of di-(2-ethylhexyl) phthalate (DEHP) in increases in allergies. The effects of DEHP have been implicated in the deflection toExpand
TRPA1 and TRPV1 activation is a novel adjuvant effect mechanism in contact hypersensitivity
We have revealed that local stimulation of sensory neurons is involved in the adjuvant effect of dibutyl phthalate (DBP) in a fluorescein isothiocyanate-induced mouse contact hypersensitivity model.Expand
Production of IgA monoclonal antibody against Shiga toxin binding subunits employing nasal-associated lymphoid tissue.
We established an IgA monoclonal antibody (mAb) against Shiga toxin 1 B subunits (Stx1B) from mouse nasal-associated lymphoid tissues (NALT) of BALB/c mice. We have developed an improved protocol inExpand