130-nm albumin-bound paclitaxel

Known as: Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Nanoparticle Paclitaxel, Nanoparticle Albumin-bound Paclitaxel 
A Cremophor EL-free, albumin-stabilized nanoparticle formulation of the natural taxane paclitaxel with antineoplastic activity. Paclitaxel binds to… (More)
National Institutes of Health

Related topics

Related topics

7 relations
ABI-007/cyclophosphamide/doxorubicinMicrotubule Processpaclitaxel protein-bound

Narrower (2)

ABI007Abraxane

Broader (2)

AlbuminsPaclitaxel

Papers overview

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Highly Cited
2014
Highly Cited
2014
SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice
DESIGN Pharmacokinetic and pharmacodynamic parameters of cremophor-paclitaxel, nab-paclitaxel (human-albumin-bound paclitaxel… (More)
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Highly Cited
2012
Highly Cited
2012
nab-Paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer.
UNLABELLED Nanoparticle albumin-bound (nab)-paclitaxel, an albumin-stabilized paclitaxel formulation, demonstrates clinical… (More)
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2009
2009
Phase II trial of weekly nab ( nanoparticle albumin-bound )-paclitaxel ( nab-paclitaxel ) ( Abraxane ) in combination with gemcitabine in patients with metastatic breast cancer ( N 0531 )
Phase II trial of weekly nab (nanoparticle albuminbound)-paclitaxel (nab-paclitaxel) (Abraxane ) in combination with gemcitabine… (More)
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Highly Cited
2008
Highly Cited
2008
Improved effectiveness of nanoparticle albumin-bound (nab) paclitaxel versus polysorbate-based docetaxel in multiple xenografts as a function of HER2 and SPARC status.
Nanoparticle albumin-bound (nab)-paclitaxel (Abraxane) is an albumin-bound 130-nm particle form of paclitaxel that demonstrated… (More)
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Highly Cited
2008
Highly Cited
2008
In vivo skin penetration of quantum dot nanoparticles in the murine model: the effect of UVR.
Ultraviolet radiation (UVR) has widespread effects on the biology and integrity of the skin barrier. Research on the mechanisms… (More)
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2008
2008
HER-2-targeted nanoparticle-affibody bioconjugates for cancer therapy.
Affibodies are a class of polypeptide ligands that are potential candidates for cellor tissuespecific targeting of drug… (More)
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Review
2007
Review
2007
Nanoparticle albumin-bound paclitaxel: a novel Cremphor-EL-free formulation of paclitaxel.
Standard formulation paclitaxel requires the use of solvents, such as Cremphor-EL, which contribute to some of the toxicities… (More)
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Review
2006
Review
2006
Albumin-bound paclitaxel: a next-generation taxane.
Taxanes are standard treatment for metastatic breast cancer; however, the solvents used as vehicles in these formulations cause… (More)
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Highly Cited
2006
Highly Cited
2006
Structural diversity in binary nanoparticle superlattices
Assembly of small building blocks such as atoms, molecules and nanoparticles into macroscopic structures—that is, ‘bottom up… (More)
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Highly Cited
2004
Highly Cited
2004
Magnetite nanoparticle-loaded anti-HER2 immunoliposomes for combination of antibody therapy with hyperthermia.
Anti-HER2 antibody can induce antitumor responses, and can be used in delivering drugs to HER2-overexpressing cancer. Previously… (More)
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