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Abraxane

National Institutes of Health

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Broader (3)

130-nm albumin-bound paclitaxelPaclitaxelpaclitaxel protein-bound
Paclitaxel 100 MG Injection [Abraxane]Paclitaxel Injection [Abraxane]

Papers overview

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2019
2019
Abstract B60: Optimization of biologic scheduling of gemcitabine and abraxane improves treatment response compared to the standard concurrent regimen in preclinical models of pancreatic cancer
Introduction: Gemcitabine (gem) and Abraxane (albumin-bound paclitaxel, abx) combination chemotherapy delivered on the same day… 
2018
2018
The PAK Inhibitor PF-3758309 Promotes the Inhibitory Effects of Multiple Chemotherapeutic Reagents on Patient-Derived Pancreatic Cancer Cell Lines
Pancreatic ductal adenocarcinoma (PDA) remains the most lethal malignancy due to lack of an effective treatment. P21-activated… 
2017
2017
Phase II study of GM-CSF secreting allogeneic pancreatic cancer vaccine (GVAX) with PD-1 blockade antibody and stereotactic body radiation therapy (SBRT) for locally advanced pancreas cancer (LAPC).
TPS4154Background: Optimal treatment strategy beyond systemic chemotherapy for LAPC remains undefined. SBRT improves local… 
2016
2016
Abstract 5115: Pre-clinical development of next generation inhibitors of the enzymes indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase as cancer immunotherapies
Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA The enzymes tryptophan 2,3-dioxygenase (TDO) and… 
2016
2016
Abstract 4681: Oseltamivir phosphate completely ablates tumor refractoriness to conventional chemotherapeutics abraxane and gemcitabine in xenografts of tumors in mouse model of human pancreatic…
Pancreatic cancer, the fourth leading cause of cancer-related death worldwide, is highly aggressive and associated with a poor… 
2015
2015
Sensitizing Band T-cell Lymphoma Cells to Paclitaxel / Abraxane – Induced Death by AS 101 via Inhibition of the VLA-4 – IL 10 – Survivin Axis
Cancer cell resistance to chemotherapy is a major concern in clinical oncology, resulting in increased tumor growth and decreased… 
2014
2014
Abstract 4578: A novel polymer-anticancer drug micelle formulation showing enhanced efficacy over Abraxane
Advances in the development of novel nanocarriers and their applications in the area of drug delivery have inspired and created… 
2013
2013
Paclitaxel albumin ( Abraxane ® ) as a substitute for docetaxel / paclitaxel for breast cancer therapy in the event of hypersensitivity reaction or contraindication to steroids
  • 2013
  • Corpus ID: 11901228
Abraxane is licensed as monotherapy for the treatment of metastatic breast cancer in patients who have failed first-line… 
2010
2010
A phase II evaluation of nab-paclitaxel in the treatment of recurrent or persistent platinum-resistant ovarian, fallopian tube, or primary peritoneal cancer: A Gynecologic Oncology Group (GOG) study.
5010 Background: Nab-paclitaxel (Abraxane, ABX) is a novel cremophor-free nanoparticle of albumin-stabilized paclitaxel, which… 
2008
2008
Automated quantitative analysis of AKT/mTOR pathway in patients treated with nanoparticle albumin-bound paclitaxel (ABI-007, Abraxane) and (sirolimus)Rapamycin
14670 Background: pp70S6K inhibition and pAkt up-regulation has been reported with mTOR inhibitors. We evaluated changes in these…