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13-azaprostanoic acid
Known as:
Cyclopentaneheptanoic acid, 2-(heptylamino)-, (1S-trans)-
National Institutes of Health
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Related topics
1 relation
Broader (1)
Prostanoic Acids
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1987
1987
Preparation and biological evaluation of a potential photoaffinity label for the prostaglandin H2/thromboxane A2 receptor.
S. Arora
,
E. J. Kattelman
,
C. Lim
,
G. L. Le Breton
,
D. Venton
Journal of Medicinal Chemistry
1987
Corpus ID: 6057971
Two aromatic azides (24 and 26) were prepared as potential photoaffinity probes for the PGH2/TXA2 receptor. The compounds are…
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1985
1985
Protective Effects of trans‐13-APT, a Thromboxane Receptor Antagonist, in Endotoxemia
L. Olanoff
,
J. Cook
,
T. Eller
,
D. Knapp
,
P. Halushka
Journal of Cardiovascular Pharmacology
1985
Corpus ID: 36098986
The effect of the thromhoxane A2prosta-glandin H2 (TxA2PGH2) receptor antagonist trans- 712-(p-hydroxyphenethylamino)-cyclopentyl…
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1985
1985
Thromboxane A2/prostaglandin H2 mobilizes calcium in human blood platelets.
L. Brace
,
D. Venton
,
G. L. Le Breton
American Journal of Physiology
1985
Corpus ID: 38396619
The present study investigated the mechanism by which thromboxane A2/prostaglandin H2 (TXA2/PGH2) stimulates platelet activation…
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1985
1985
Acetyl glycerylphosphorylcholine aggregates human platelets through two distinct pathways, both dependent on arachidonic acid metabolism.
D. Macconi
,
G. Morzenti
,
M. Livio
,
C. Morelli
,
G. Cassina
,
G. Remuzzi
Laboratory investigation; a journal of technical…
1985
Corpus ID: 23102850
Acetyl glyceryl ether phosphorylcholine (AGEPC) is a mediator of inflammation and anaphylaxis, released from IgE-sensitized…
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1985
1985
Reversal of thromboxane A2/prostaglandin H2 and ADP-induced calcium release in intact platelets.
L. Brace
,
D. Venton
,
G. L. Le Breton
American Journal of Physiology
1985
Corpus ID: 24025745
We previously demonstrated that thromboxane A2 and/or prostaglandin H2 (TXA2/PGH2), ADP, and A23187 cause calcium mobilization in…
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1984
1984
Antagonism of Prostanoid‐Induced Vascular Contraction by 13‐Azaprostanoic Acid (13‐APA)
P. Horn
,
J. Kohli
,
G. Lebreton
,
D. Venton
Journal of Cardiovascular Pharmacology
1984
Corpus ID: 29103855
Isometric contractions in vitro of helically eut strips of canine mesenteric arteries (O.D. = 0.6–1 mm) were recorded in the…
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Review
1984
Review
1984
Modulation of vascular thrombosis by products of arachidonic acid metabolism.
K. Wu
,
E. Hall
,
A. Papp
Clinical physiology and biochemistry
1984
Corpus ID: 34381092
It has been postulated that metabolites of the arachidonic acid pathway exert an important influence on hemostasis and thrombosis…
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1983
1983
2-(6-carboxyhexyl)cyclopentanone hexylhydrazone. A potent and time-dependent inhibitor of platelet aggregation.
N. Ghali
,
D. Venton
,
S. Hung
,
G. L. Le Breton
Journal of Medicinal Chemistry
1983
Corpus ID: 5948030
Two new azaprostanoids, a hydrazone (3) and hydrazide (4), have been prepared by the condensation of 2-(6-carboxyhexyl…
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1981
1981
Increased platelet prostaglandin and thromboxane synthesis in diabetes mellitus.
P. Halushka
,
R. Rogers
,
+4 authors
J. Colwell
Hormone and metabolic research. Supplement series
1981
Corpus ID: 34420112
Platelets obtained from some diabetic patients show enhanced in vitro platelet aggregation. These studies were designed to…
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1979
1979
13-Azaprostanoic acid: Aspecific antagonist ofthehumanblood platelet thromboxane/endoperoxide receptor
G. Lebreton
,
D. L. VENTONt
,
P. V. HALUSHKAt
1979
Corpus ID: 86154482
A newlysynthesized 13-aza derivative of prostanoic acid (13-APA) specifically inhibited humanplatelet aggregation induced…
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