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125IUdR

Known as: 125-I Deoxyuridine 
A radiopharmaceutical comprised of a thymidine analog, 5-iodo-2''-deoxyuridine (idoxuridine), labelled with the Auger electron emitter Iodine 125… 
National Institutes of Health

Papers overview

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2006
2006
Genome-wide gene expression changes in normal human fibroblasts in response to low-LET gamma-radiation and high-LET-like 125IUdR exposures.
Functional genomics studies were carried out to characterize the transcriptional response of normal human fibroblasts to ionizing… 
1998
1998
Iodo-2'-deoxyuridine (IUdR) and 125IUdR loaded biodegradable microspheres for controlled delivery to the brain.
The aim of this work was to develop sustained local release systems for radioiodinated iodo-2'-deoxyuridine (125IUdR) from… 
1991
1991
Selective uptake of toxic nucleoside (125IUdR) by resistant cancer.
We report uptake of a thymidine analogue 125-Iodine-5-iodo-2'-deoxyuridine (125IUdR) by nude mice bearing human xenografts of… 
Highly Cited
1989
Highly Cited
1989
Radiotoxicity of 5-[123I]iodo-2'-deoxyuridine in V79 cells: a comparison with 5-[125I]iodo-2'-deoxyuridine.
The toxic effects of the short-lived (T 1/2 = 13.2 h) Auger-electron-emitting isotope 123I, incorporated in the form of 123IUdR… 
Highly Cited
1985
Highly Cited
1985
Systemic administration of recombinant interleukin 2 stimulates in vivo lymphoid cell proliferation in tissues.
Recent work in our laboratory has demonstrated that the repeated injections of high doses of recombinant interleukin 2 (IL 2) can… 
Highly Cited
1984
Highly Cited
1984
Afferent lymph and lymph borne cells: their influence on lymph node function.
Highly Cited
1977
Highly Cited
1977
5-125I-iododeoxyuridine as prototype for radionuclide therapy with Auger emitters
MANY of the physical and biological requirements for treating cancer with internally emitting radionuclides are met by 5-125I… 
Highly Cited
1977
Highly Cited
1977
Specificities of killing by cytotoxic lymphocytes generated in vivo and in vitro to syngeneic SV40 transformed cells.
Cell-mediated immunity to SV40-transformed C3H and C3H-SW cell lines was measured by using both 51Cr and 125IUdR release assays… 
1976
1976
The distribution and fate of blood‐borne 125 iudr‐labelled tumour cells in immune syngeneic rats
Radiolabelled sarcoma cells injected into the tail veins of normal rats were held up almost exclusively in the lung, and were not… 
Highly Cited
1974
Highly Cited
1974
Demonstration of radiosensitization of hypoxic cells in solid tumours by metronidazole.
Abstract Significant radiosensitization of naturally occurring hypoxic cells by metronidazole (“Flagyl”) is demonstrated in two… 
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