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11,12,15-trihydroxyeicosatrienoic acid

Known as: 11,12,15-TETA 
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Stimulation of vascular endothelial cells with agonists such as acetylcholine (ACh) or bradykinin or with shear stress activates… 
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2009
2009
Arachidonic acid (AA) is metabolized by endothelial 15-lipoxygenase (15-LO) to several vasodilatory eicosanoids such as 11,12,15… 
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2008
2008
Arachidonic acid (AA) causes endothelium-dependent smooth muscle hyperpolarizations and relaxations that are mediated by a 15… 
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2008
2008
Previous studies indicate that 11,12,15-trihydroxyeicosatrienoic acid (11,12,15-THETA), an endothelium-derived hyperpolarizing… 
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Highly Cited
2006
Highly Cited
2006
ACh stimulates arachidonic acid (AA) release from membrane phospholipids of vascular endothelial cells (ECs). In rabbit aorta, AA… 
2006
2006
Objective—Aortic 15-lipoxygenase (15-LO) metabolizes arachidonic acid (AA) to 15-hydroperoxyeicosatetraenoic acid, which is then… 
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2005
2005
We recently reported that the lipoxygenase product 11,12,15-trihydroxyeicosatrienoic acid (THETA) mediates arachidonic acid (AA… 
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Highly Cited
2004
Highly Cited
2004
Abstract—Arachidonic acid induces an endothelium-dependent relaxation of the rabbit aorta that is blocked by lipoxygenase… 
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2003
2003
Rabbit aortic endothelium metabolizes arachidonic acid (AA) by the 15-lipoxygenase pathway to vasodilatory eicosanoids… 
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Highly Cited
1998
Highly Cited
1998
A number of endothelium-derived relaxing factors have been identified including nitric oxide, prostacyclin, and the… 
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