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11,12,15-trihydroxyeicosatrienoic acid

Known as: 11,12,15-TETA 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

8,11,14-Eicosatrienoic Acid
analogs & derivatives

Papers overview

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2015
2015
Inhibition of Vascular Smooth Muscle Cell Migration by an Endothelium‐derived 15‐Lipoxygenase Metabolite, 11,12,15‐Trihydroxyeicosatrienoic Acid
11,12,15‐Trihydroeicosatrienoic acid (11,12,15‐THETA) is an endothelium‐derived 15‐lipoxygenase (LO) metabolite of arachidonic… 
2012
2012
Endothelial nitric oxide and 15-lipoxygenase-1 metabolites independently mediate relaxation of the rabbit aorta.
2012
2012
Abstract 507: G Proteins are Required for Lipoxygenase EDHF Activity of Rabbit Arterial Smooth Muscle Cells
Arachidonic acid 15-lipoxygenase (15-LO) metabolites function as endothelium-derived hyperpolarizing factors in rabbit and human… 
Review
2009
Review
2009
Hyperpolarizing Factor in Rabbit Arteries as an Acid-stable Endothelium-derived Acid 13-Hydroxy-14 , 15-epoxyeicosatrienoic Identification of Regulation , and Signaling : Lipids and Lipoproteins…
10.1074/jbc.M109.025627 Access the most updated version of this article at doi: . JBC Affinity Sites Find articles, minireviews… 
2008
2008
Identification of 15-hydroxy-11,12-epoxyeicosatrienoic acid as a vasoactive 15-lipoxygenase metabolite in rabbit aorta.
Arachidonic acid (AA) causes endothelium-dependent smooth muscle hyperpolarizations and relaxations that are mediated by a 15… 
2008
2008
11(R),12(S),15(S)-trihydroxyeicosa-5(Z),8(Z),13(E)-trienoic acid: an endothelium-derived 15-lipoxygenase metabolite that relaxes rabbit aorta.
Previous studies indicate that 11,12,15-trihydroxyeicosatrienoic acid (11,12,15-THETA), an endothelium-derived hyperpolarizing… 
2008
2008
Age-related decrease in 15-lipoxygenase contributes to reduced vasorelaxation in rabbit aorta.
Rabbit 15-lipoxygenase-1 (15-LO-1) oxygenates arachidonic acid (AA) into 15-hydroperoxyeicosatetraenoic acid, which is then… 
2006
2006
Reticulocyte 15-Lipoxygenase-I Is Important in Acetylcholine-Induced Endothelium-Dependent Vasorelaxation in Rabbit Aorta
Objective—Aortic 15-lipoxygenase (15-LO) metabolizes arachidonic acid (AA) to 15-hydroperoxyeicosatetraenoic acid, which is then… 
2003
2003
Interleukin-13 Upregulates Vasodilatory 15-Lipoxygenase Eicosanoids in Rabbit Aorta
Objective—Vasorelaxation of rabbit aorta is mediated by factors released from the vascular endothelium. In the aortic endothelium… 
2000
2000
Role of 11,12,15-Trihydroxyeicosatrienoic Acid as a New Endothelium-Derived Relaxing Factor
3 The endothelium regulates vascular tone through the release of relaxing factors including nitric oxide, prostacyclin… 
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