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11,12,15-trihydroxyeicosatrienoic acid
Known as:
11,12,15-TETA
National Institutes of Health
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Related topics
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2 relations
Broader (1)
8,11,14-Eicosatrienoic Acid
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Role of arachidonic acid lipoxygenase metabolites in the regulation of vascular tone.
Yuttana Chawengsub
,
K. Gauthier
,
W. Campbell
American Journal of Physiology. Heart and…
2009
Corpus ID: 31096834
Stimulation of vascular endothelial cells with agonists such as acetylcholine (ACh) or bradykinin or with shear stress activates…
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2009
2009
Identification of 13-Hydroxy-14,15-epoxyeicosatrienoic Acid as an Acid-stable Endothelium-derived Hyperpolarizing Factor in Rabbit Arteries*
Yuttana Chawengsub
,
K. Gauthier
,
+4 authors
W. Campbell
Journal of Biological Chemistry
2009
Corpus ID: 24607427
Arachidonic acid (AA) is metabolized by endothelial 15-lipoxygenase (15-LO) to several vasodilatory eicosanoids such as 11,12,15…
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2008
2008
Identification of 15-hydroxy-11,12-epoxyeicosatrienoic acid as a vasoactive 15-lipoxygenase metabolite in rabbit aorta.
Yuttana Chawengsub
,
Nitin T. Aggarwal
,
+5 authors
W. Campbell
American Journal of Physiology. Heart and…
2008
Corpus ID: 5886891
Arachidonic acid (AA) causes endothelium-dependent smooth muscle hyperpolarizations and relaxations that are mediated by a 15…
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2008
2008
11(R),12(S),15(S)-trihydroxyeicosa-5(Z),8(Z),13(E)-trienoic acid: an endothelium-derived 15-lipoxygenase metabolite that relaxes rabbit aorta.
K. Gauthier
,
Yuttana Chawengsub
,
+4 authors
W. Campbell
American Journal of Physiology. Heart and…
2008
Corpus ID: 16574574
Previous studies indicate that 11,12,15-trihydroxyeicosatrienoic acid (11,12,15-THETA), an endothelium-derived hyperpolarizing…
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Highly Cited
2006
Highly Cited
2006
Role of phospholipase C and diacylglyceride lipase pathway in arachidonic acid release and acetylcholine-induced vascular relaxation in rabbit aorta.
Xin Tang
,
Erik M Edwards
,
B. Holmes
,
J. Falck
,
W. Campbell
American Journal of Physiology. Heart and…
2006
Corpus ID: 1027385
ACh stimulates arachidonic acid (AA) release from membrane phospholipids of vascular endothelial cells (ECs). In rabbit aorta, AA…
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2006
2006
Reticulocyte 15-Lipoxygenase-I Is Important in Acetylcholine-Induced Endothelium-Dependent Vasorelaxation in Rabbit Aorta
Xin Tang
,
B. Holmes
,
K. Nithipatikom
,
C. Hillard
,
H. Kuhn
,
W. Campbell
Arteriosclerosis, Thrombosis and Vascular Biology
2006
Corpus ID: 1297987
Objective—Aortic 15-lipoxygenase (15-LO) metabolizes arachidonic acid (AA) to 15-hydroperoxyeicosatetraenoic acid, which is then…
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2005
2005
Cyclooxygenase- and lipoxygenase-dependent relaxation to arachidonic acid in rabbit small mesenteric arteries.
David X. Zhang
,
K. Gauthier
,
Yuttana Chawengsub
,
B. Holmes
,
W. Campbell
American Journal of Physiology. Heart and…
2005
Corpus ID: 8886065
We recently reported that the lipoxygenase product 11,12,15-trihydroxyeicosatrienoic acid (THETA) mediates arachidonic acid (AA…
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Highly Cited
2004
Highly Cited
2004
Apamin-Sensitive K+ Currents Mediate Arachidonic Acid-Induced Relaxations of Rabbit Aorta
K. Gauthier
,
N. Spitzbarth
,
Erik M Edwards
,
W. Campbell
HYPERTENSION
2004
Corpus ID: 12504946
Abstract—Arachidonic acid induces an endothelium-dependent relaxation of the rabbit aorta that is blocked by lipoxygenase…
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2003
2003
11,12,15-Trihydroxyeicosatrienoic acid mediates ACh-induced relaxations in rabbit aorta.
W. Campbell
,
N. Spitzbarth
,
K. Gauthier
,
S. Pfister
American Journal of Physiology. Heart and…
2003
Corpus ID: 16729227
Rabbit aortic endothelium metabolizes arachidonic acid (AA) by the 15-lipoxygenase pathway to vasodilatory eicosanoids…
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Highly Cited
1998
Highly Cited
1998
Identification of the 11,14,15- and 11,12,15-Trihydroxyeicosatrienoic Acids as Endothelium-derived Relaxing Factors of Rabbit Aorta*
S. Pfister
,
N. Spitzbarth
,
K. Nithipatikom
,
W. Edgemond
,
J. Falck
,
W. Campbell
Journal of Biological Chemistry
1998
Corpus ID: 40560809
A number of endothelium-derived relaxing factors have been identified including nitric oxide, prostacyclin, and the…
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