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Nicotinamide adenine dinucleotide (NAD)

Known as: DPN, Nicotinamide-Adenine Dinucleotide, Dinucleotide, Dihydronicotinamide Adenine 
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature… 
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (27)

1,4,5,6-tetrahydronicotinamide adenine dinucleotide1-benzyl-1,4-dihydronicotinamide2'-deoxynicotinamide adenine dinucleotide3,4-dimethylpyridine adenine dinucleotide
4-nitro-4'-aminodiphenyl sulfoneIn BloodNADHProcess of secretion

Broader (6)

Adenine NucleotidesCoenzymesNucleotideschemical cofactor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice
With no approved pharmacological treatment, nonalcoholic fatty liver disease (NAFLD) is now the most common cause of chronic… 
Highly Cited
2009
Highly Cited
2009
Electrochemical sensing and biosensing platform based on chemically reduced graphene oxide.
In this paper, the characterization and application of a chemically reduced graphene oxide modified glassy carbon (CR-GO/GC… 
Highly Cited
2008
Highly Cited
2008
The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor
SummaryBackground FK866 is a potent inhibitor or NAD synthesis. This first-in-human study was performed to determine the maximum… 
Review
2004
Review
2004
Biochemistry of exercise-induced metabolic acidosis.
The development of acidosis during intense exercise has traditionally been explained by the increased production of lactic acid… 
Review
2003
Review
2003
Histone Deacetylases: Unique Players in Shaping the Epigenetic Histone Code
Abstract: The epigenome is defined by DNA methylation patterns and the associated posttranslational modifications of histones… 
Review
1988
Review
1988
Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury.
Highly Cited
1986
Highly Cited
1986
Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide.
To determine the biochemical basis of the oxidant-induced injury of cells, we have studied early changes after exposure of P388D1… 
Highly Cited
1973
Highly Cited
1973
Peroxisomal and Mitochondrial Defects in the Cerebro-Hepato-Renal Syndrome
The cerebro-hepato-renal syndrome is a rare familial malady with cerebral, renal, and skeletal abnormalities, severe hypotonia… 
Highly Cited
1962
Highly Cited
1962
Microsomal triphosphopyridine nucleotide-cytochrome c reductase of liver.
Review
1948
Review
1948
The extinction coefficients of the reduced band of pyridine nucleotides.
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