10-deacetyltaxol

Known as: 10-deacetyl-7-epi-taxol, 10-deacetyl-7-epitaxol, Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha))- 
An analog of paclitaxel with antineoplastic activity. 10-Deacetyltaxol binds to and stabilizes the resulting microtubules, thereby inhibiting… Expand
National Institutes of Health

Papers overview

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2016
2016
Burkholderia contaminans MS14 shows significant antimicrobial activities against plant and animal pathogenic fungi and bacteria… Expand
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2012
2012
This method development was to confirm the fatal ingestion of toxic yew plant material in postmortem samples (stomach content… Expand
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2011
2011
N-substituted benzenesulfonamides, incorporating the N-amino-, N-hydroxy- and N-methoxy-moieties at the sulfonamide zinc binding… Expand
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2006
2006
BackgroundTaxol is an effective antineoplastic agent, originally extracted from the bark of Taxus brevifolia with a low yield… Expand
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2001
2001
Bioassay-guided fractionation of the extracts from the insect pathogenic fungus Cordyceps nipponica BCC 1389 led to the isolation… Expand
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1995
1995
Glucuronidation of N-hydroxy arylamines is thought to be a necessary step in their initiation of bladder cancer. This was… Expand
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1994
1994
In vivo voltammetry was performed in rat brain cortex and in rat brain endothelial constitutive NO-synthase preparations. The use… Expand
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1992
1992
The covalent binding of the N-acetoxy-, N-hydroxy-, and nitro derivatives of the food-borne carcinogen 2-amino-1-methyl-6… Expand
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1990
1990
The ion permeability of transmembrane channels formed by the linear gramicidins is altered by amino acid sequence substitutions… Expand
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1981
1981
Activity-guided, chromatographic fractionation for a polar extract of Taxus wallichiana Zucc. (originally identified as… Expand
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