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10-deacetyltaxol

Known as: 10-deacetyl-7-epi-taxol, 10-deacetyl-7-epitaxol, Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha))- 
An analog of paclitaxel with antineoplastic activity. 10-Deacetyltaxol binds to and stabilizes the resulting microtubules, thereby inhibiting… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Efficient and selective methods for covalent derivatization of graphene are needed because they enable tuning of graphene’s… Expand
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2011
2011
N-substituted benzenesulfonamides, incorporating the N-amino-, N-hydroxy- and N-methoxy-moieties at the sulfonamide zinc binding… Expand
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2007
2007
The three-dimensional structure of a unique polymorph of the anticancer drug paclitaxel (Taxol) is established using solid state… Expand
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2005
2005
Base hydrolysis of BiO(ClO4) yields ClO4- salts of the novel nonabismuth polyoxo cation Bi9(mu3-O)8(mu3-OH)6(5+); ethanolysis… Expand
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Highly Cited
2001
Highly Cited
2001
Bioassay-guided fractionation of the extracts from the insect pathogenic fungus Cordyceps nipponica BCC 1389 led to the isolation… Expand
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1995
1995
Glucuronidation of N-hydroxy arylamines is thought to be a necessary step in their initiation of bladder cancer. This was… Expand
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1994
1994
In vivo voltammetry was performed in rat brain cortex and in rat brain endothelial constitutive NO-synthase preparations. The use… Expand
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Highly Cited
1992
Highly Cited
1992
The covalent binding of the N-acetoxy-, N-hydroxy-, and nitro derivatives of the food-borne carcinogen 2-amino-1-methyl-6… Expand
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1990
1990
The ion permeability of transmembrane channels formed by the linear gramicidins is altered by amino acid sequence substitutions… Expand
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Highly Cited
1981
Highly Cited
1981
Activity-guided, chromatographic fractionation for a polar extract of Taxus wallichiana Zucc. (originally identified as… Expand
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