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10-deacetyltaxol

Known as: 10-deacetyl-7-epi-taxol, 10-deacetyl-7-epitaxol, Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha))- 
An analog of paclitaxel with antineoplastic activity. 10-Deacetyltaxol binds to and stabilizes the resulting microtubules, thereby inhibiting… 
National Institutes of Health

Related topics

Related topics

3 relations
Microtubule ProcessNCIt Antineoplastic Agent Terminology

Broader (1)

Taxoids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Aerobic biodegradation of high explosive hexahydro-1,3,5- trinitro-1,3,5-triazine by Janibacter cremeus isolated from contaminated soil
To evaluate the ability of Janibacter cremeus a soil bacterium isolated from explosive contaminated site in degradation of… 
2015
2015
Pilot studies on scale-up biocatalysis of 7-β-xylosyl-10-deacetyltaxol and its analogues by an engineered yeast
Paclitaxel content in yew tree is extremely low, causing a worldwide shortage of this important anticancer drug. Yew tree can… 
2011
2011
Fragmentation features of intermolecular cross-linked peptides using N-hydroxy- succinimide esters by MALDI- and ESI-MS/MS for use in structural proteomics.
The use of mass spectrometry coupled with chemical cross-linking of proteins has become one of the most useful tools for proteins… 
2005
2005
Solvolytic routes to new nonabismuth hydroxy- and alkoxy-oxo complexes: synthesis, characterization and solid-state structures of novel nonabismuth polyoxo cations Bi9(mu3-O)8(mu3-OR)6 5+ (R = H, Et…
Base hydrolysis of BiO(ClO4) yields ClO4- salts of the novel nonabismuth polyoxo cation Bi9(mu3-O)8(mu3-OH)6(5+); ethanolysis… 
1999
1999
Taxumairol M: A New Bicyclic Taxoid from Seeds of Taxus mairei
1 2 epi 3 5 4 Taxus mairei 4 
1996
1996
Rearrangements of Exogenus 17beta-Hydroxy- 17alpha-methylandrosta-1,4-dien-3-one in Cultures of the Green Alga T76 Scenedesmus quadricauda.
1994
1994
Site-specific enzymatic hydrolysis of taxanes at C-10 and C-13.
The production of large amounts of paclitaxel for use as an anticancer treatment has been a challenging problem because of the… 
1990
1990
Distinction between dipolar and inductive effects in modulating the conductance of gramicidin channels.
The ion permeability of transmembrane channels formed by the linear gramicidins is altered by amino acid sequence substitutions… 
1984
1984
Fluorescent probes based on styrylpyridinium derivatives: optical properties and membrane binding.
1981
1981
Identification of the modified nucleotides produced by covalent photoaddition of hydroxymethyltrimethylpsoralen to RNA.
The reaction between RNA and 4'hydroxymethyl-4,5',8-trimethylpsoralen has been studied. Both natural RNA and synthetic RNAs were… 
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