FAQ

1-hexylcarbamoyl-5-fluorouracil

Known as: 1(2H)-Pyrimidinecarboxamide, 5-fluoro-N-hexyl-3,4-dihydro-2,4-dioxo-, Carmofur, HCFU 
An antimetabolite (pyrimidine analogue) antineoplastic derivative of 5-fluorouracil. (NCI)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2017
0102019762017

Related topics

Related topics

4 relations

Broader (2)

Antineoplastic AgentsFluorouracil

Narrower (1)

Mifurol
analogs & derivatives

Related mentions per year

Related mentions per year

1942-2018
19401960198020002020
1-hexylcarbamoyl-5-fluorouracil
Antineoplastic Agents
Fluorouracil
Mifurol
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action
Breast cancer is the second leading cause of cancer related deaths among females worldwide. Berbamine (BER), a kind of bis… (More)
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Highly Cited
2001
Highly Cited
2001
Randomized, controlled trial of lateral node dissection vs. nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy.
PURPOSE The effectiveness of preoperative radiation therapy for advanced lower rectal carcinoma to preserve the function of… (More)
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1989
1989
Hyperthermia enhances the in vitro activity of 1-hexylcarbamoyl-5-fluorouracil compared to that of 5-fluorouracil.
The synergic effects on HeLa cells between 1-hexylcarbamoyl-5-fluorouracil (HCFU), a lipophilic masked compound of 5-fluorouracil… (More)
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1988
1988
UFT is more antineoplastic against gastric carcinoma than 5-fluorouracil, 1-(2-tetrahydrofuryl)-5-fluorouracil and 1-hexylcarbamoyl-5-fluorouracil.
The sensitivity of human gastric cancer tissue to 5-fluorouracil (5-FU) and its analogues 1-(2-tetrahydrofuryl)-5-fluorouracil… (More)
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1988
1988
Colorectal carcinoma in vitro is more sensitive to 1-hexylcarbamoyl-5-fluorouracil compared with six other antitumor drugs: carboquone, Adriamycin, mitomycin C, aclacinomycin A, cisplatin, 5…
The sensitivity to 1-hexylcarbamoyl-5-fluorouracil (HCFU) of 25 colorectal cancer tissues was compared with that of six antitumor… (More)
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1987
1987
1-Hexylcarbamoyl-5-fluorouracil is more cytostatic than 5-fluorouracil against human tumors in vitro.
The sensitivity of HeLa cells and 15 human tumors, including eight gastric cancers, five colorectal cancers and two lung cancers… (More)
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1984
1984
[Clinical evaluation of 1-hexylcarbamoyl-5-fluorouracil (HCFU) in hepatocellular carcinoma].
1-Hexylcarbamoyl-5-fluorouracil (HCFU) was administered orally to 63 patients with hepatocellular carcinoma (HCC) at a daily dose… (More)
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1981
1981
Excretion of 1-hexylcarbamoyl-5-fluorouracil in urine of mice.
Excretion and metabolites in urine and feces of mice after oral administration of l-hexylcarbamoyl-5-fluorouracil-6-14C (14C-HCFU… (More)
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1978
1978
Metabolic fate of 1-hexylcarbamoyl-5-fluorouracil in rats.
1. The metabolic fate of a new antitumour agent, 1-hexylcarbamoyl-5-fluoro [6-14C]uracil (14C-HCFU) in rats after oral… (More)
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1976
1976
Antitumor activity of 1-hexylcarbamoyl-5-fluorouracil in a variety of experimental tumors.
Antitumor activity of 1-hexylcarbamoyl-5-fluorouracil against various tumors was examined. Therapeutic ratio (ILSmax/ILS30) in L… (More)
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