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1-hexylcarbamoyl-5-fluorouracil

Known as: 1(2H)-Pyrimidinecarboxamide, 5-fluoro-N-hexyl-3,4-dihydro-2,4-dioxo-, CARMOFUR, HCFU 
An antimetabolite (pyrimidine analogue) antineoplastic derivative of 5-fluorouracil. (NCI)
National Institutes of Health

Papers overview

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2017
2017
Reactive oxygen species (ROS) are generated in the cell through multiple mechanisms. Intracellular ROS are rapidly detoxified by… Expand
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2016
2016
ABSTRACT It is now well established that bacterial infections are often associated with biofilm phenotypes that demonstrate… Expand
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Highly Cited
2013
Highly Cited
2013
The expression of acid ceramidase (AC) – a cysteine amidase that hydrolyses the proapoptotic lipid ceramide – is abnormally high… Expand
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2013
2013
Acid ceramidase (AC) is an intracellular cysteine amidase that catalyzes the hydrolysis of the lipid messenger ceramide. By… Expand
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Highly Cited
2009
Highly Cited
2009
BackgroundBreast cancer is the second leading cause of cancer related deaths among females worldwide. Berbamine (BER), a kind of… Expand
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2009
2009
IL-27 was first discovered as a factor supporting initial Th1 immune responses. Subsequent studies revealed that this cytokine… Expand
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Highly Cited
2006
Highly Cited
2006
Random copolymeric micelles composed of N-isopropylacrylamide (NIPAAM) and N-vinylpyrrolidone (VP) cross-linked with N,N… Expand
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Highly Cited
2001
Highly Cited
2001
PURPOSE: The effectiveness of preoperative radiation therapy for advanced lower rectal carcinoma to preserve the function of… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The goal of the current study was use metaanalysis to evaluate the effect of postoperative adjuvant chemotherapy after… Expand
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1999
1999
BACKGROUND Oral 5-fluorouracil and its prodrugs (tegafur, carmofur) is now being studied for adjuvant chemotherapy of curatively… Expand
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