Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

1-Naphthylisothiocyanate

Known as: Naphthalene, 1-isothiocyanato-, 1 Naphthylisothiocyanate, alpha Naphthylisothiocyanate 
A tool for the study of liver damage which causes bile stasis and hyperbilirubinemia acutely and bile duct hyperplasia and biliary cirrhosis… Expand
National Institutes of Health

Related topics

Related topics

9 relations

Narrower (2)

2-naphthylisothiocyanate4-N,N-dimethylamino-1-naphthylisothiocyanate
In Bloodagonistsanalogs & derivativesantagonists & inhibitors
Expand

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Investigations of free anthraquinones from rhubarb against alpha-naphthylisothiocyanate-induced cholestatic liver injury in rats.
The protective effects of anthraquinones from Rhubarb, a Chinese herbal medicine, consisting of the root and rhizome of Rheum… Expand
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Exploration of Emodin to treat alpha-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway.
Emodin, 1,3,8-trihydroxy-6-methyl-anthraquinone, is an anthraquinone derivative from the roots of Rheum officinale Baill that has… Expand
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
A toxicogenomics approach for early assessment of potential non-genotoxic hepatocarcinogenicity of chemicals in rats.
For assessing carcinogenicity in animals, it is difficult and costly, an alternative strategy has been desired. We explored the… Expand
Is this relevant?
2008
2008
Bile acids metabonomic study on the CCl4- and alpha-naphthylisothiocyanate-induced animal models: quantitative analysis of 22 bile acids by ultraperformance liquid chromatography-mass spectrometry.
Bile acids (BAs) are crucial for the diagnosis, follow-up, and prognostics of liver and intestinal disorders and other diseases… Expand
  • table 1
  • figure 1
  • figure 3
  • table 3
  • figure 4
Is this relevant?
2004
2004
Limited role for CXC chemokines in the pathogenesis of alpha-naphthylisothiocyanate-induced liver injury.
Alpha-naphthylisothiocyanate (ANIT) is a hepatotoxin that causes severe neutrophilic inflammation around portal tracts and bile… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis.
Farnesoid X receptor (FXR) is a bile acid-activated transcription factor that is a member of the nuclear hormone receptor… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate.
The metabolite profiles from livers of toxin-treated rats were investigated using high resolution 1H NMR spectroscopy of aqueous… Expand
Is this relevant?
Highly Cited
2001
Highly Cited
2001
NMR and pattern recognition studies on the time-related metabolic effects of alpha-naphthylisothiocyanate on liver, urine, and plasma in the rat: an integrative metabonomic approach.
We present here a novel integrative metabonomic approach to probe toxic effects of drugs in experimental animals using alpha… Expand
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Hepatic OV-6 expression in human liver disease and rat experiments: evidence for hepatic progenitor cells in man.
BACKGROUND/AIMS/METHODS Since in rat experiments, activation of progenitor cells is seen in conditions associated with hepatocyte… Expand
Is this relevant?
1984
1984
Serum gamma glutamyl transferase as a specific indicator of bile duct lesions in the rat liver.
Serum gamma-glutamyl transferase (GGT), a marker of hepatic injury used extensively in humans, has been used rarely in rats… Expand
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE