FAQ

1-Naphthylisothiocyanate

Known as: Naphthalene, 1-isothiocyanato-, 1 Naphthylisothiocyanate, alpha Naphthylisothiocyanate 
A tool for the study of liver damage which causes bile stasis and hyperbilirubinemia acutely and bile duct hyperplasia and biliary cirrhosis… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2015
012319772015

Related topics

Related topics

10 relations

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2-naphthylisothiocyanate4-N,N-dimethylamino-1-naphthylisothiocyanate
In Bloodadministration & dosageagonistsantagonists & inhibitors
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Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
1-Naphthylisothiocyanate
agonists
chemical synthesis
standards characteristics
4-N,N-dimethylamino-1-naphthylisothiocyanate
In Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Investigations of free anthraquinones from rhubarb against alpha-naphthylisothiocyanate-induced cholestatic liver injury in rats.
The protective effects of anthraquinones from Rhubarb, a Chinese herbal medicine, consisting of the root and rhizome of Rheum… (More)
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Highly Cited
2000
Highly Cited
2000
Characterization of inducible nature of MRP3 in rat liver.
We found previously that expression of multidrug resistance-associated protein (MRP) 3 is induced in a mutant rat strain (Eisai… (More)
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1999
1999
ANIT-induced disruption of biliary function in rat hepatocyte couplets.
alpha-Naphthylisothiocyanate (ANIT) induces intrahepatic cholestasis in rats, involving damage to biliary epithelial cells; our… (More)
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1995
1995
1-naphthylisothiocyanate-induced elevation of biliary glutathione.
1-Naphthylisothiocyanate (ANIT) has been used for many years to study cholangiolitic hepatotoxicity in laboratory animals… (More)
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1995
1995
Naphthylisothiocyanate disposition in bile and its relationship to liver glutathione and toxicity.
1-Naphthylisothiocyanate (ANIT), but not 2-naphthylisothiocyanate (BNIT), produces cholangiolitic hepatitis in rats after a… (More)
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1993
1993
Induction of multidrug resistance gene expression during cholestasis in rats and nonhuman primates.
P-glycoprotein, an energy-dependent plasma membrane drug-efflux pump capable of reducing the intracellular concentration of a… (More)
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1991
1991
Involvement of glutathione in 1-naphthylisothiocyanate (ANIT) metabolism and toxicity to isolated hepatocytes.
1-Naphthylisothiocyanate (ANIT) is a model compound which causes cholestasis in laboratory animals. Various biochemical and… (More)
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1991
1991
An antibody to neutrophils attenuates alpha-naphthylisothiocyanate-induced liver injury.
alpha-Naphthylisothiocyanate (ANIT) causes cholestasis and injury to bile duct epithelium and hepatic parenchymal cells in rats… (More)
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1991
1991
Protection against alpha-naphthylisothiocyanate-induced liver injury by decreased hepatic non-protein sulfhydryl content.
alpha-Naphthylisothiocyanate (ANIT) injures bile duct epithelium and hepatic parenchymal cells in rats. It is commonly believed… (More)
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1986
1986
1-Naphthylisothiocyanate-induced permeability of hepatic tight junctions to proteins.
We have studied the early action of 1-naphthylisothiocyanate (ANIT) in relation to its effect on the permeability barrier formed… (More)
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