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1-Naphthylisothiocyanate
Known as:
Naphthalene, 1-isothiocyanato-
, 1 Naphthylisothiocyanate
, alpha Naphthylisothiocyanate
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A tool for the study of liver damage which causes bile stasis and hyperbilirubinemia acutely and bile duct hyperplasia and biliary cirrhosis…
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National Institutes of Health
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9 relations
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2-naphthylisothiocyanate
4-N,N-dimethylamino-1-naphthylisothiocyanate
In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
NMR and pattern recognition studies on the time-related metabolic effects of alpha-naphthylisothiocyanate on liver, urine, and plasma in the rat: an integrative metabonomic approach.
N. Waters
,
E. Holmes
,
A. Williams
,
C. Waterfield
,
R. Farrant
,
J. Nicholson
Chemical Research in Toxicology
2001
Corpus ID: 33428707
We present here a novel integrative metabonomic approach to probe toxic effects of drugs in experimental animals using alpha…
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2001
2001
Effect of melatonin on changes in hepatic antioxidant enzyme activities in rats treated with α‐naphthylisothiocyanate
Y. Ohta
,
M. Kongo
,
T. Kishikawa
Journal of Pineal Research
2001
Corpus ID: 33146506
We have reported that melatonin protects against α‐naphthylisothiocyanate (ANIT)‐induced acute liver injury in rats by preventing…
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1999
1999
An association between lipid peroxidation and alpha-naphthylisothiocyanate-induced liver injury in rats.
M. Kongo
,
Y. Ohta
,
K. Nishida
,
E. Sasaki
,
N. Harada
,
I. Ishiguro
Toxicology Letters
1999
Corpus ID: 27513067
1996
1996
Abnormal lipoproteins in the ANIT-treated rat: a transient and reversible animal model of intrahepatic cholestasis.
J. W. Chisholm
,
P. Dolphin
Journal of Lipid Research
1996
Corpus ID: 12676692
The alpha-naphthylisothiocyanate (ANIT)-treated rat was evaluated as a model for lipoprotein metabolism in cholestatic liver…
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Highly Cited
1995
Highly Cited
1995
Naphthylisothiocyanate disposition in bile and its relationship to liver glutathione and toxicity.
P. A. Jean
,
R. Roth
Biochemical Pharmacology
1995
Corpus ID: 40707829
1991
1991
Protection against alpha-naphthylisothiocyanate-induced liver injury by decreased hepatic non-protein sulfhydryl content.
L. Dahm
,
R. Roth
Biochemical Pharmacology
1991
Corpus ID: 22277996
1983
1983
No increase of biliary permeability in ethinylestradiol-treated rats
H. Jaeschke
,
H. Krell
,
E. Pfaff
1983
Corpus ID: 196243366
1981
1981
alpha-Naphthylisothiocyanate induced alterations in hepatic drug metabolizing enzymes and liver morphology: implications concerning anticarcinogenesis.
T. Leonard
,
J. Popp
,
M. Graichen
,
J. Dent
Carcinogenesis
1981
Corpus ID: 45211740
Alpha-naphthylisothiocyanate (ANIT) is a biliary toxin with anticarcinogenic properties. The studies described were designed to…
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Highly Cited
1972
Highly Cited
1972
Early appearance of serum -fetoprotein during hepatocarcinogenesis as a function of age of rats and extent of treatment with 3'-methyl-4-dimethylaminoazobenzene.
R. Kroes
,
G. Williams
,
J. Weisburger
Cancer Research
1972
Corpus ID: 23842614
The early appearance of serum alpha-fetoprotein (AFP) during hepatocarcinogenesis as a function of age of rats and extent of…
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1965
1965
Demonstration of bile stasis in the mouse by a direct and an indirect method.
G. Plaa
,
B. A. Becker
Journal of applied physiology
1965
Corpus ID: 37920718
Cannulation of the common bile duct of the mouse has been effected. Bile flow rates and bile pigment concentrations have been…
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