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1-Naphthylisothiocyanate

Known as: Naphthalene, 1-isothiocyanato-, 1 Naphthylisothiocyanate, alpha Naphthylisothiocyanate 
A tool for the study of liver damage which causes bile stasis and hyperbilirubinemia acutely and bile duct hyperplasia and biliary cirrhosis… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Emodin, 1,3,8-trihydroxy-6-methyl-anthraquinone, is an anthraquinone derivative from the roots of Rheum officinale Baill that has… Expand
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Highly Cited
2006
Highly Cited
2006
Expression of the farnesoid X receptor (FXR; NR1H4) is limited to the liver, intestine, kidney, and adrenal gland. However, the… Expand
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Highly Cited
2003
Highly Cited
2003
Farnesoid X receptor (FXR) is a bile acid-activated transcription factor that is a member of the nuclear hormone receptor… Expand
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Review
2003
Review
2003
Cholestasis may result from a failure in bile secretion in hepatocytes or ductular cells, or from a blockade to the free bile… Expand
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Highly Cited
2002
Highly Cited
2002
The metabolite profiles from livers of toxin-treated rats were investigated using high resolution 1H NMR spectroscopy of aqueous… Expand
Highly Cited
2001
Highly Cited
2001
We present here a novel integrative metabonomic approach to probe toxic effects of drugs in experimental animals using alpha… Expand
Highly Cited
2001
Highly Cited
2001
MRP2 is a canalicular transporter in hepatocytes mediating the transport of a wide spectrum of amphipathic compounds. This… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND/AIMS/METHODS Since in rat experiments, activation of progenitor cells is seen in conditions associated with hepatocyte… Expand
Highly Cited
1992
Highly Cited
1992
Hepatocyte growth factor, a potent mitogen for mature hepatocytes in vitro, seems to function as a hepatotrophic factor for liver… Expand
Highly Cited
1991
Highly Cited
1991
alpha-Naphthylisothiocyanate (ANIT) causes cholestasis and injury to bile duct epithelium and hepatic parenchymal cells in rats… Expand