1,3,4-oxadiazole
National Institutes of Health
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Compounds containing 1,3,4-oxadiazole ring in their structure are characterised by multidirectional biological activity. Their…
BACKGROUND
The literature shows that bisthioether and 1,3,4-oxadiazole derivatives exhibit a wide variety of biological…
We describe 1,3,4-oxadiazole-containing hydroxamates (2) and 2-aminoanilides (3) as histone deacetylase inhibitors. Among them…
There has been considerable interest in the development of novel compounds with anticonvulsant, antidepressant, analgesic, anti…
A new series of high brightness and luminance efficient poly(p-phenylenevinylene) (PPV)-based electroluminescent (EL) polymers…
Design of 5-(3,5-di-tert-butyl-4-hydroxyphenyl)-1,3,4-thiadiazoles, -1,3,4-oxadiazoles, and -1,2,4-triazoles as orally-active, nonulcerogenic antiinflammatory agents. To discover dual inhibitors of 5-lipoxygenase (LO) and cyclooxygenase (CO) with improved pharmacokinetic properties, we have…