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Phytoconstituents and therapeutic uses of Rheum emodi wall. ex Meissn
Abstract Rhubarb (Rheum emodi, family Polygonaceae) has been traditionally used as diuretic, liver stimulant, purgative/cathartic, stomachic, anticholesterolaemic, antitumour, antiseptic andExpand
Antihepatotoxic activity of seeds of Cichorium intybus.
TLDR
The histopathological study of the liver was carried out, wherein the methanolic fraction and compound AB-IV showed almost complete normalization of the tissues as neither fatty accumulation nor necrosis was observed. Expand
Hepatoprotective activity of two plants belonging to the Apiaceae and the Euphorbiaceae family.
TLDR
The methanolic extracts showed the most significant hepatoprotective activity comparable with standard drug silymarin, and other extracts namely petroleum ether and acetone also exhibited a potent activity. Expand
Scropolioside-D2 and harpagoside-B: two new iridoid glycosides from Scrophularia deserti and their antidiabetic and antiinflammatory activity.
TLDR
Five iridoid glycosides, including the two new compounds scropolioside-D(2) (1) and harpagoside-B (2), were isolated from the aerial parts of Scrophularia deserti DEL and were found to possess significant antidiabetic and antiinflammatory activity. Expand
Advances in preparation and characterization of chitosan nanoparticles for therapeutics
Context: Polymers have been largely explored for the preparation of nanoparticles due to ease of preparation and modification, large gene/drug loading capacity, and biocompatibility. Various methodsExpand
Three new diterpenes and the biological activity of different extracts of Jasonia montana
TLDR
Three new diterpenes were isolated from the aerial parts of Jasonia montana (Asteraceae), and the previously reported 5,7,3′-trihydroxy-3,6,4′-trimethoxy flavone designated as centaureidin was also isolated and characterized from this source. Expand
Preparation, characterization, in vivo and biochemical evaluation of brain targeted Piperine solid lipid nanoparticles in an experimentally induced Alzheimer’s disease model
TLDR
P-80-PIP-SLN has shown therapeutic effects in Alzheimer via reducing the oxidative stress and reducing the cholinergic degradation at 2 mg/kg dose equivalent. Expand
Synthesis and antihepatotoxic activity of some heterocyclic compounds containing the 1,4-dioxane ring system.
TLDR
The structure activity relationship (SAR) was studied, and where the flavonoid analogues containing a hydroxy methyl group at position-2" in the dioxane ring exhibited superior antihepatotoxic activity in comparison to coumarin derivatives. Expand
Anti-hepatotoxic activity of cichotyboside, a sesquiterpene glycoside from the seeds of Cichorium intybus
TLDR
Cichotyboside exhibited a significant anti-hepatotoxic activity against CCl4 induced toxicity in Wistar rats, wherein it reduced the elevated levels of liver enzymes such as serum glutamate oxaloacetate transaminase (SGOT) and SGPT and increased the level of total albumin against intoxicated control. Expand
Hepatoprotective activity of Luffa echinata fruits.
TLDR
The petroleum ether, acetone and methanolic extracts of the fruits of Luffa echinata Roxb showed a significant hepatoprotective activity comparable with those of Silymarin. Expand
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