1,3-propane sultone

Known as: 3-Hydroxy-1-propanesulfonic Acid gamma-Sultone, gamma-Propane Sultone, 1,2-Oxathiolane 2,2-Dioxide 
A synthetic, colorless liquid or white crystalline solid that is readily soluble in water and many organic solvents such as ketones, esters and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1968-2018
024619682018

Papers overview

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2016
2016
The Pig-a assay is a useful in vivo mutation detecting test and is easier to perform than the in vivo transgenic mutation assay… (More)
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2015
2015
Validation of the Pig-a gene mutation assay has been based mainly on studies in male rodents. To determine if the mutagen-induced… (More)
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2014
2014
To evaluate whether blood-based genotoxicity endpoints can provide temporal and dose-response data within the low-dose… (More)
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2012
2012
1,3-Propane sultone (1,3-PS) is a directly alkylating, genotoxic and carcinogenic substance. In rats, 1,3-PS induces local and… (More)
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2011
2011
An international collaborative trial was established to systematically investigate the merits and limitations of a rat in vivo… (More)
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1981
1981
Fourteen chemicals of varied uses were tested for carcinogenicity by oral administration in male and female Charles River CD rats… (More)
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1978
1978
Transforming DNA was exposed to either beta-propiolactone or 1,3-propane sultone and then used for transformation of competent… (More)
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1977
1977
To evaluate its usefulness for detection of mutagenicity and oncogenicity of chemicals, the frequency of chromosome aberrations… (More)
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1976
1976
To determine correlations between the biological action pattern and chemical reactivity of alkylating agents, the rate constants… (More)
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