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International Agency for Research on Cancer.
TLDR
Applications for a training fellowship in 2014-2015 are invited from postdoctoral scientists who intend to pursue a career in cancer research and wish to complete their training in those aspects of cancer research related to the Agency’s mission. Expand
Cancer chemopreventive activity of Xanthohumol, a natural product derived from hop.
TLDR
Together, the data provide evidence for the potential application of XN as a novel, readily available chemopreventive agent, and clinical investigations are warranted once efficacy and safety in animal models have been established. Expand
IARC monographs on the evaluation of carcinogenic risks to humans. Solar and ultraviolet radiation.
TLDR
The presenters include Lawrence Banks, International Centre for Genetic Engineering and Biotechnology, Italy, Frederick A. Beland, National Center for Toxicological Research, USA, and James A. Bond, Chemico-Biological Interactions, USA. Expand
Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers.
TLDR
The overall effects of common CYP polymorphisms were found to be moderate in terms of penetrance and relative risk, with odds ratios ranging from 2 to 10. Expand
Olive-oil consumption and health: the possible role of antioxidants.
TLDR
Evidence is presented that it is the unique profile of the phenolic fraction, along with high intakes of squalene and the monounsaturated fatty acid, oleic acid, which confer its health-promoting properties. Expand
Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis.
TLDR
Nitric oxide (NO) and other oxygen radicals produced in infected and inflamed tissues could contribute to the process of carcinogenesis by different mechanisms, which are discussed on the basis of authors' studies on liver fluke infection and cholangiocarcinoma development. Expand
The antioxidant/anticancer potential of phenolic compounds isolated from olive oil.
TLDR
It is demonstrated that the antioxidant phenolic compounds present in olive oil are potent inhibitors of free radical generation by the faecal matrix, indicating that the study of the inter-relation between reactive oxygen species and dietary antioxidants is an area of great promise for elucidating mechanisms of colorectal carcinogenesis and possible future chemopreventive strategies. Expand
Characterization of alkyl phenols in cashew (Anacardium occidentale) products and assay of their antioxidant capacity.
TLDR
The data presented in this study indicates that this waste product along with CNSL, both of which contain high contents of anacardic acids, could be better utilized in functional food formulations and may represent a cheap source of cancer chemopreventive agents. Expand
Nuclear Factor κB Is a Molecular Target for Sulforaphane-mediated Anti-inflammatory Mechanisms*
TLDR
A potent decrease in lipopolysaccharide (LPS)-induced secretion of pro-inflammatory and pro-carcinogenic signaling factors in cultured Raw 264.7 macrophages after SFN treatment is reported, providing novel evidence that anti-inflammatory mechanisms contribute to sulforaphane-mediated cancer chemoprevention. Expand
Phenolic compounds and squalene in olive oils: the concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignansand squalene.
TLDR
The aim of this study was to evaluate the phenolic antioxidant and squalene content in a range of olive and seed oils, and both the nature and source of olive oil consumed should be differentiated in ascertaining cancer risk. Expand
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