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1,1-dimethylheptyl-11-hydroxytetrahydrocannabinol

Known as: 7-hydroxy-delta-6-tetrahydrocannabinoldimethylheptyl, DEXANABINOL, 5'(1,1-dimethylheptyl)-7-hydroxyhexahydrocannabinol 
A synthetic, terpene-based cannabinoid derivative devoid of cannabinoid receptors 1 and 2 agonist activity and with potential neuroprotective… 
National Institutes of Health

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HU 211
NCIt Antineoplastic Agent Terminology

Papers overview

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Review
2011
Review
2011
Use of magnesium in traumatic brain injury
Highly Cited
2006
Highly Cited
2006
Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial
Highly Cited
2003
Highly Cited
2003
Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor.
The cannabinoid analog abnormal cannabidiol [abn-cbd; (-)-4-(3-3,4-trans-p-menthadien-[1,8]-yl)-olivetol] does not bind to CB(1… 
Review
2003
Review
2003
Promising strategies to minimize secondary brain injury after head trauma
ObjectiveTo review novel therapeutic approaches in the treatment of severe traumatic brain injury. DesignEighty-three studies… 
Highly Cited
2003
Highly Cited
2003
Differential distribution of functional cannabinoid CB1 receptors in the mouse gastroenteric tract.
Highly Cited
2002
Highly Cited
2002
Dexanabinol (HU-211) in the treatment of severe closed head injury: a randomized, placebo-controlled, phase II clinical trial.
OBJECTIVE To establish the safety of intravenous dexanabinol in severe head injury. DESIGN Prospective, randomized, double… 
Highly Cited
1999
Highly Cited
1999
Dexanabinol; a novel neuroprotective drug in experimental focal cerebral ischemia
Highly Cited
1997
Highly Cited
1997
Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors.
Previous studies indicate that the CB1 cannabinoid receptor antagonist, N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4… 
Highly Cited
1997
Highly Cited
1997
Relative efficacies of cannabinoid CB1 receptor agonists in the mouse brain.
1997
1997
Clinical pharmacokinetics of escalating i.v. doses of dexanabinol (HU-211), a neuroprotectant agent, in normal volunteers.
The pharmacokinetics of dexanabinol (HU-211), a synthetic, nonpsychotropic cannabinoid with neuroprotectant action, was evaluated… 
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