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Metabotropic P2Y receptors subfamily consists of eight functional mammalian receptors. Specifically, P2Y1, P2Y6 and P2Y11… Expand During exercise, skeletal muscle produces reactive oxygen species (ROS) via NADPH oxidase (NOX2) while inducing cellular… Expand Platelet‐derived growth factor receptor‐α‐positive (PDGFRα+) interstitial cells in detrusor muscles may participate in post… Expand Although previous reports have suggested that P2Y1 receptors (P2Y1Rs) are involved in cutaneous nociceptive signaling, it remains… Expand Traumatic brain injury (TBI) is the leading cause of death and disability in children and young adults. Neuroprotective agents… Expand Background In the present study, we further characterize the purinergic receptors mediating the inhibitory junction potential… Expand Background and purpose: This study was undertaken to compare the analgesic activity of antagonists acting at P2X1, P2X7, and… Expand Extracellular ADP is known to play many important physiological roles. In this study, we identified the P2Y(13) receptor in a rat… Expand Stimulation of receptors for either ATP or adenosine leads to physiologic changes in retinal pigment epithelial (RPE) cells that… Expand In comparison to other classes of cell surface receptors, the medicinal chemistry at P2X (ligand-gated ion channels) and P2Y (G… Expand