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(22R)-22-hydroxycholesterol

Known as: 22(R)-hydroxycholesterol, 22(R)OH cholesterol, 22R-hydroxycholesterol 
 
National Institutes of Health

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22-hydroxycholesterol

Papers overview

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Highly Cited
2010
Highly Cited
2010
Antiproliferative effect of LXR agonists T0901317 and 22(R)-hydroxycholesterol on multiple human cancer cell lines.
Previously, we and other groups reported that liver X receptor (LXR) agonists T0901317, 22(R)-hydroxycholesterol, and 24(S… Expand
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2009
2009
Green tea polyphenols inhibit testosterone production in rat Leydig cells.
This study investigated the acute effects of green tea extract (GTE) and its polyphenol constituents, (-)-epigallocatechin-3… Expand
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Highly Cited
2004
Highly Cited
2004
Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: implications for biliary tract carcinogenesis.
Cyclooxygenase-2 (COX-2), which is expressed by cholangiocytes in biliary tract disorders, has recently been implicated in… Expand
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2004
2004
Rosiglitazone upregulates caveolin-1 expression in THP-1 cells through a PPAR-dependent mechanism Published, JLR Papers in Press, August 16, 2004. DOI 10.1194/jlr.M400049-JLR200
Peroxisome proliferator-activated receptor γ (PPARγ) activation or overexpression induces caveolin-1 (cav-1) expression in… Expand
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Highly Cited
2003
Highly Cited
2003
Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene…
Fatty acid metabolism is transcriptionally regulated by two reciprocal systems: peroxisome proliferator-activated receptor (PPAR… Expand
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Highly Cited
2001
Highly Cited
2001
Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter.
In an attempt to identify transcription factors which activate sterol-regulatory element-binding protein 1c (SREBP-1c… Expand
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Highly Cited
2001
Highly Cited
2001
Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha).
The cholesterol 7alpha-hydroxylase gene (CYP7A1) plays an important role in regulation of bile acid biosynthesis and cholesterol… Expand
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Highly Cited
2000
Highly Cited
2000
Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor.
Tangier disease, a condition characterized by low levels of high density lipoprotein and cholesterol accumulation in macrophages… Expand
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Highly Cited
2000
Highly Cited
2000
Human White/Murine ABC8 mRNA Levels Are Highly Induced in Lipid-loaded Macrophages
To identify genes that are transcriptionally activated when human macrophages accumulate excess lipids, we employed the mRNA… Expand
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1993
1993
Inhibition of hormone-stimulated steroidogenesis in cultured Leydig tumor cells by a cholesterol-linked phosphorothioate oligodeoxynucleotide antisense to diazepam-binding inhibitor.
The polypeptide diazepam-binding inhibitor (DBI) has been previously shown to stimulate testicular Leydig, adrenocortical, and… Expand
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