Transcriptomic Analysis Reveals a Bifurcated Terephthalate Degradation Pathway in Rhodococcus sp. Strain RHA1

@article{Hara2006TranscriptomicAR,
  title={Transcriptomic Analysis Reveals a Bifurcated Terephthalate Degradation Pathway in Rhodococcus sp. Strain RHA1},
  author={Hirofumi Hara and Lindsay D. Eltis and Julian E. Davies and William W. Mohn},
  journal={Journal of Bacteriology},
  year={2006},
  volume={189},
  pages={1641 - 1647},
  url={https://api.semanticscholar.org/CorpusID:12157737}
}
Results indicate that PTH is degraded solely via thePCA pathway, whereas TPA is degraded via a bifurcated pathway that additionally includes the catechol branch of the PCA pathway.
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51 References

Transcriptomic Assessment of Isozymes in the Biphenyl Pathway of Rhodococcus sp. Strain RHA1

A suite of catabolic enzymes for biphenyl and alkyl-benzenes in RHA1 is delineated, which is larger than previously recognized and which may serve as a model for catabolism in other environmentally important bacteria having large genomes.

Catabolism of Benzoate and Phthalate in Rhodococcus sp. Strain RHA1: Redundancies and Convergence

Analysis of completed bacterial genomes indicates that the convergent beta-ketoadipate pathway and some aspects of its genetic organization are characteristic of rhodococci and related actinomycetes.

Characterization of the Isophthalate Degradation Genes of Comamonas sp. Strain E6

The results indicated that the iphACBD genes are essential for the catabolism of IPA in E6, and suggested that IPADO is a two-component dioxygenase that consists of a terminal oxygenase component (IphA) and a reductase component(IphD) and that iphB encodes the 1,5-DCD dehydrogenase.

Molecular and biochemical analysis of phthalate and terephthalate degradation by Rhodococcus sp. strain DK17.

Characterization of the Terephthalate Degradation Genes of Comamonas sp. Strain E6

TPADO was strongly suggested to be a two-component dioxygenase which consists of the terminal oxygenase component (TphA2 and TphA3) and the reductase (TPHA1), and tphB codes for the DCD dehydrogenase.

The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse

Overall, RHA1 appears to have evolved to simultaneously catabolize a diverse range of plant-derived compounds in an O2-rich environment and is established as an important model for studying actinomycete physiology.

Novel Organization of the Genes for Phthalate Degradation from Burkholderia cepacia DBO1

Strains deleted for ophD are able to transport phthalate into the cell at rates equivalent to that of the wild-type organism, showing that this gene is not required for growth onphthalate.

Characterization of Transcriptional Regulatory Genes for Biphenyl Degradation in Rhodococcus sp. Strain RHA1

The notion that bphS and bphT encode a sensor kinase and a response regulator, respectively, of a two-component regulatory system is supported, as well as the notion that at least BphS is indispensably responsible for the growth of RHA1 on biphenyl.

Molecular analysis of isophthalate and terephthalate degradation by Comamonas testosteroni YZW-D.

Analysis of the catabolic pathways by which isophthalate and terephthalate are degraded demonstrated that a cis-dihydrodiol intermediate is involved in both pathways.

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Results suggested that RHA1 would break down at least some PCB congeners into smaller molecules to a considerable extent.
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