Stabilization of p18 by deubiquitylase CYLD is pivotal for cell cycle progression and viral replication

@article{Li2021StabilizationOP,
  title={Stabilization of p18 by deubiquitylase CYLD is pivotal for cell cycle progression and viral replication},
  author={Yue-Qin Li and Feng Shi and Jianmin Hu and Longlong Xie and Lin Zhao and Min Tang and Xiangjian Luo and Mao Ye and Hui Zheng and Min Zhou and Na Liu and Ann M. Bode and Jia Fan and Jian Zhou and Qiang Gao and Shuangjian Qiu and Weizhong Wu and Xin Zhang and Weihua Liao and Ya Cao},
  journal={NPJ Precision Oncology},
  year={2021},
  volume={5},
  url={https://api.semanticscholar.org/CorpusID:232083651}
}
CYLD is identified as a deubiquitinase of p18, which binds to and removes the K48-linked polyubiquitylation chains conjugated onto p 18, thus stabilizing the p18 protein and directly stabilizing p18 to regulate the cellular G1/S transition.
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12 Citations

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61 References

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