Extra-toes (Xt) homozygous mutant mice demonstrate a role for the Gli-3 gene in the development of the forebrain.

@article{Franz1994ExtratoesH,
  title={Extra-toes (Xt) homozygous mutant mice demonstrate a role for the Gli-3 gene in the development of the forebrain.},
  author={Thomas Franz},
  journal={Acta anatomica},
  year={1994},
  volume={150 1},
  pages={
          38-44
        },
  url={https://api.semanticscholar.org/CorpusID:41805560}
}
Observations suggest that the proper expression of the Gli-3 gene in the forebrain is a prerequisite for the normal development of the telencephalon and later of the cerebral cortex.
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