Skip to search formSkip to main contentSkip to account menu

zeniplatin

Known as: (2,2-bis(aminomethyl)-1,3-propanediol-N,N')(1,1-cyclobutanedicarboxylato(2')-O,O')platinum(II), cis-(2,2-Bis(aminomethyl)-1,3-propanediol)(1,1-cyclobutanedicarboxylato)platinum 
A third-generation, water-soluble platinum compound. (NCI)
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Carboplatin
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Resistance of Seven Platinum Compounds Relationship of Cellular Glutathione to the Cytotoxicity and Updated
The role of glutathione (GSH) in the effectiveness of and resistance to 7 platinum compounds [5 Pt(II) and 2 Pt(IV) drugs] was… 
2005
2005
Phase II trial of zeniplatin (CL 286 558), a new patinum compound, in patients with advanced ovarian cancer previously treated with organoplatinum-based therapy
There is a critical need to find new chemotherapeutic agents that are active in platinum-refractory ovarian cancer. A phase II… 
2004
2004
Pharmacokinetic evaluation of zeniplatin in humans
Zeniplatin, a more water-soluble organoplatinum than cisplatin, was evaluated for clinical pharmacology in the context of a phase… 
1997
1997
Zeniplatin in advanced malignant melanoma and renal cancer: phase II studies with unexpected nephrotoxicity
Abstract The antitumor activity of zeniplatin, a third-generation, water-soluble platinum compound that has shown broad… 
1995
1995
A Phase II Trial of Zeniplatin in Metastatic Melanoma
A third-generation platinum analogue, zeniplatin, was administered at a dose of 145 mg/m2 intravenously over 60–90 minutes every… 
1993
1993
国外开发中新药：抗肿瘤药 Zeniplatin
Review
1992
Review
1992
The current status of new platinum analogs.
Nine platinum analogs are currently in clinical development, including three that contain the diaminocyclohexane substituent and… 
1991
1991
Phase I clinical and pharmacokinetic study of zeniplatin, a new platinum complex.
Forty-six patients with refractory solid malignancies received the new platinum complex [2,2-bis(aminomethyl)-1,3-propanediol-N-N… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)