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zampanolide

Known as: (+)-zampanolide 
National Institutes of Health

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1 relation

Broader (1)

Macrolides

Papers overview

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2019
2019
Synthesis and antiproliferative evaluation of new zampanolide mimics.
(-)-Zampanolide is a marine microtubule-stabilizing macrolide that has been shown by in vitro experiments to be a promising… 
2019
2019
Synthesis, conformational preferences, and biological activity of conformational analogues of the microtubule-stabilizing agents, (-)-zampanolide and (-)-dactylolide.
Zampanolide and dactylolide are microtubule-stabilizing polyketides possessing potent cytotoxicity towards a variety of cancer… 
2018
2018
Chasing "Zampanalogs": Advancing the Synthesis of the Zampanolide Macrocycle
(-)-Zampanolide (1), a natural product isolated from a marine sponge, is a microtubule-stabilizing agent that exhibits activity… 
2018
2018
Optimized synthesis and antiproliferative activity of desTHPdactylolides.
2013
2013
Conformational preferences of zampanolide and dactylolide.
The solution conformation behavior of the macrolide core of microtubule-stabilizing agents (-)-zampanolide and (-)-dactylolide… 
2013
2013
Methods for studying microtubule binding site interactions: zampanolide as a covalent binding agent.
2011
2011
Synthèse énantiosélective d’1,2 et 1,3-diamines et Développement de réactions multicomposants dans des conditions oxydantes
Ce projet scientifique porte sur le developpement de nouvelles voies d’acces a des composes azotes hautement fonctionnalises en s… 
2011
2011
Shotgun and targeted MS analyses pinpoint the zampanolide-tubulin interacting site
Microtubule Stabilizing Agents (MSA) are one of the most successful antitumour drugs used in clinical treatment of neoplasic… 
2010
2010
Total synthesis of (-)-dactylolide.
The development of an approach leading to the total synthesis of dactylolide is described. The key features of this route include… 
2002
2002
Studies toward the synthesis of (-)-zampanolide: preparation of N-acyl hemiaminal model systems.
[structure: see text] Synthesis of N-acyl hemiaminal model systems related to the side chain of the antitumor natural product… 
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