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zaleplon

Known as: 3'-(3-cyanopyrazolo(1,5-alpha)pyrimidin-7-yl)-N-ethylacetanilide, N-(3-(3-cyanopyrazolo(1,5-a)pyrimidin-7-yl)phenyl)-N-ethylacetamide, 3'-(3-Cyanopyrazolo(1,5-a)pyrimidin-7-yl)-N-ethylacetanilide 
A nonbenzodiazepine from the pyrazolopyrimidine class with hypnotic, sedative, anxiolytic, and muscle relaxant properties. Zaleplon interacts with… 
National Institutes of Health

Related topics

Related topics

18 relations

Broader (5)

AcetamidesAnticonvulsantsGABA ModulatorsHypnotics and Sedatives

Narrower (4)

CL 284,846L 846SKP-1041Sonata
CYP3A7 protein, humanCentral Nervous System Depression [PE]Drug AllergyGABA B Agonists [MoA]

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
GABAA-positive modulator selective discriminative stimulus effects of 1,1,1-trichloroethane vapor.
2010
2010
Benzodiazepine discontinuation among community-dwelling older people: a population-based cohort study
HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they… 
Review
2007
Review
2007
Update on the safety considerations in the management of insomnia with hypnotics: incorporating modified-release formulations into primary care.
OBJECTIVE From a safety perspective, several issues require assessment when a decision is made to prescribe a sleep medication… 
2004
2004
Direct injection, column switching-liquid chromatographic technique for the estimation of rabeprazole in bioequivalence study.
Highly Cited
2004
Highly Cited
2004
Characterization of the Interaction of Indiplon, a Novel Pyrazolopyrimidine Sedative-Hypnotic, with the GABAA Receptor
Clinically used benzodiazepine and nonbenzodiazepine sedative-hypnotic agents for the treatment of insomnia produce their… 
2003
2003
γ-Hydroxybutyric Acid and Diazepam Antagonize a Rapid Increase in GABAA Receptors α4 Subunit mRNA Abundance Induced by Ethanol Withdrawal in Cerebellar Granule Cells
Both benzodiazepines and γ-hydroxybutyric acid (GHB) are used to treat alcohol withdrawal syndrome. The molecular basis for this… 
2003
2003
Oral citalopram and reboxetine challenge tests before and after selective antidepressant treatment.
2002
2002
Effect of zaleplon on learning and memory in rats
Abstract. Although structurally not a benzodiazepine, 3′-(3-cyanopyrazolo [1,5-a] pyrimidin-7-yl)-N-ethylacetamide (zaleplon) it… 
2001
2001
Different types of GABAA receptors may mediate the anticonflict and response rate-decreasing effects of zaleplon, zolpidem, and midazolam in squirrel monkeys
Abstract.Rationale: The role of different types of GABAA receptors in mediating anticonflict and response rate-decreasing effects… 
2000
2000
Differentiating benzodiazepine‐ and barbiturate‐like discriminative stimulus effects of lorazepam, diazepam, pentobarbital, imidazenil and zaleplon in two‐ versus three‐lever procedures
Previous studies found that animals trained to discriminate pentobarbital show a relatively inclusive generalization profile… 
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