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zabofloxacin

Known as: 1-Cyclopropyl-6-fluoro-7-(8-(methoxyimino)-2,6-diazaspiro(3.4)octan-6-yl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic Acid 
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

DW-224a

Broader (1)

Fluoroquinolones

Papers overview

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2018
2018
[New antibiotics in infection treatment].
The introduction of new molecules with antimicrobial activity is an opportunity for modern antibiotic therapy in the era of… 
2017
2017
Avarofloxacin, nemonoxacin, and zabofloxacin
Avarofloxacin and zabofloxacin are conventional fluoroquinolones with a fluorine atom inserted at position 6 in the quinolone… 
2016
2016
Zabofloxacin for chronic bronchitis.
Treatment of lower respiratory tract infection poses as an ongoing challenge among respiratory tract diseases. Bacterial… 
Review
2016
Review
2016
Chemical structure and pharmacokinetics of novel quinolone agents represented by avarofloxacin, delafloxacin, finafloxacin, zabofloxacin and nemonoxacin
Quinolones are potent antimicrobial agents with a basic chemical structure of bicyclic ring. Fluorine atom at position C-6 and… 
2015
2015
The potentiation and broadening the effect of low molecular hypoglycemic drugs through interaction with some CNS stimulant molecules
This dissertation submitted for the partial fulfilment of the requirements for the degree of Doctor of Phylosophy in… 
Review
2011
Review
2011
Fluorescence detection of Zabofloxacin, a novel fluoroquinolone antibiotic, in plasma, bile, and urine by HPLC: the first oral and intravenous applications in a pharmacokinetic study in rats.
PURPOSE To develop an HPLC method using fluorescence detection for the pharmacokinetic evaluation of levels of zabofloxacin, a… 
2011
2011
Determination of zabofloxacin in rat plasma by liquid chromatography with mass spectrometry and its application to pharmacokinetic study.
2010
2010
DNA gyrase and topoisomerase IV are dual targets of zabofloxacin in Streptococcus pneumoniae
Funding:ThisstudywassupportedbyanunrestrictedgrantfromSanofi-aventis(Midrand,SouthAfrica).Inaddition,routinesurveil-lance isolate… 
2008
2008
Analyses Supporting Phase 2 Clinical Trial Dose Selection for Zabofloxacin in Community-acquired Pneumonia
Objective: To conduct analyses in support of dose selection for zabofloxacin in Phase 2 community acquired pneumonia (CAP… 
2008
2008
Comparative in Vitro Activity of Zabofloxacin (DW-224a) Tested Against Multidrug-Resistant Neisseria gonorrhoeae
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