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welwitindolinone A isonitrile

 
National Institutes of Health

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Indole Alkaloids

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Highly Cited
2006
Highly Cited
2006
Total synthesis of (+/-)-welwitindolinone a isonitrile.
A highly stereoselective total synthesis of the alkaloid natural product welwitindolinone A isonitrile has been completed. The… Expand
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Highly Cited
1993
Highly Cited
1993
Selection of the Optimal Nonexercise Stress for the Evaluation of Ischemic Regional Myocardial Dysfunction and Malperfusion Comparison of Dobutamine and Adenosine Using Echocardiography and 99mTc…
BackgroundThe mechanisms of action of exercise-simulating and vasodilator stressors support their combination with imaging… Expand
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Highly Cited
1992
Highly Cited
1992
Subcellular distribution and analysis of technetium-99m-MIBI in isolated perfused rat hearts.
To address the apparent discrepancy between cultured cells and whole heart preparations, Langendorff-perfused rat hearts loaded… Expand
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Highly Cited
1990
Highly Cited
1990
Uptake and retention of hexakis (2-methoxyisobutyl isonitrile) technetium(I) in cultured chick myocardial cells. Mitochondrial and plasma membrane potential dependence.
The fundamental myocellular uptake and retention mechanisms of hexakis (2-methoxyisobutyl isonitrile) technetium(I) (Tc-MIBI), a… Expand
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Highly Cited
1990
Highly Cited
1990
Are the kinetics of technetium-99m methoxyisobutyl isonitrile affected by cell metabolism and viability?
To investigate the role of cell viability and metabolism on the myocardial kinetics of a new tracer, technetium-99m… Expand
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Highly Cited
1990
Highly Cited
1990
Quantification of area at risk during coronary occlusion and degree of myocardial salvage after reperfusion with technetium-99m methoxyisobutyl isonitrile.
Serial myocardial imaging with technetium-99m methoxyisobutyl isonitrile (99mTc-MIBI) has been proposed for evaluating myocardial… Expand
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Highly Cited
1989
Highly Cited
1989
Technetium-99m hexakis 2-methoxyisobutyl isonitrile: human biodistribution, dosimetry, safety, and preliminary comparison to thallium-201 for myocardial perfusion imaging.
The biodistribution, dosimetry, and safety of a new myocardial imaging agent, 99mTc-hexakis-2-methoxyisobutyl isonitrile… Expand
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Highly Cited
1989
Highly Cited
1989
Feasibility of tomographic 99mTc-hexakis-2-methoxy-2-methylpropyl-isonitrile imaging for the assessment of myocardial area at risk and the effect of treatment in acute myocardial infarction.
99mTc-hexakis-2-methoxy-2-methylpropyl-isonitrile (Tc-Sestamibi), a new myocardial perfusion radiopharmaceutical, was injected… Expand
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Highly Cited
1988
Highly Cited
1988
Myocardial kinetics of technetium-99m-hexakis-2-methoxy-2-methylpropyl-isonitrile.
To study the potential usefulness of technetium-99m hexakis-2-methoxy-2-methylpropyl-isonitrile (Tc-MIBI) as a cardiac perfusion… Expand
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Highly Cited
1988
Highly Cited
1988
Quantification of myocardial infarction during coronary occlusion and myocardial salvage after reperfusion using cardiac imaging with technetium-99m hexakis 2-methoxyisobutyl isonitrile.
Myocardial imaging with technetium-99m hexakis 2-methoxyisobutyl isonitrile was investigated as a means to assess myocardial… Expand
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