• Publications
  • Influence
ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation.
TLDR
The once-in-a-lifetime treatment with Abciximab Intracoronary for acute coronary syndrome and a second dose intravenously for atrial fibrillation is recommended for adults with high blood pressure. Expand
2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology.
TLDR
The If Inhibitor Ivabradine in Patients With Coronary Artery Disease and Left Ventricular Dysfunction is evaluated as well as patients with Diabetes mellitus for Optimal management of Multivessel disease. Expand
Genetic determinants of response to clopidogrel and cardiovascular events.
TLDR
Among patients with an acute myocardial infarction who were receiving clopidogrel, those carrying CYP2C19 loss-of-function alleles had a higher rate of subsequent cardiovascular events than those who were not, particularly marked among the patients undergoing percutaneous coronary intervention. Expand
Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: the Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the
Guidelines and Expert Consensus Documents summarize and evaluate all currently available evidence on a particular issue with the aim of assisting physicians in selecting the best managementExpand
Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis.
TLDR
Among patients treated with clopidogrel for percutaneous coronary intervention, carriage of even 1 reduced-function CYP2C19 allele appears to be associated with a significantly increased risk of major adverse cardiovascular events, particularly stent thrombosis. Expand
A validated prediction model for all forms of acute coronary syndrome:estimating the risk of 6-month postdischarge death in an international registry
TLDR
The GRACE 6-month postdischarge prediction model is a simple, robust tool for predicting mortality in patients with ACS and Clinicians may find it simple to use and applicable to clinical practice. Expand
Management of acute coronary syndromes. Variations in practice and outcome; findings from the Global Registry of Acute Coronary Events (GRACE).
TLDR
The GRACE study reveals substantial differences in the management of patients based on hospital type and geographical location and will determine whether such variations translate into differences in longer term outcomes. Expand
Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia
TLDR
Among patients with elevated triglyceride levels despite the use of statins, the risk of ischemic events, including cardiovascular death, was significantly lower among those who received 2 g of icosapent ethyl twice daily than amongThose who received placebo. Expand
Acute coronary syndromes without chest pain, an underdiagnosed and undertreated high-risk group: insights from the Global Registry of Acute Coronary Events.
TLDR
Patients with ACSs who present without chest pain are frequently misdiagnosed and undertreated, and each dominant presenting symptom independently identifies a population that is at increased risk of dying. Expand
Intervention in acute coronary syndromes: do patients undergo intervention on the basis of their risk characteristics? The Global Registry of Acute Coronary Events (GRACE)
TLDR
A risk-averse strategy to angiography appears to be widely adopted and systematic and accurate risk stratification may allow higher-risk patients to be selected for revascularisation procedures, in contrast to current international practice. Expand
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