wedelolactone

Known as: 7-methoxy-5,11,12-trihydroxy-coumestan 
 
National Institutes of Health

Papers overview

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2013
2013
Wedelolactone (WEL), a major coumestan ingredient in Wedelia chinensis, has been used to treat septic shock, hepatitis and venom… (More)
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2013
2013
Signal transducers and activators of transcription 1 (STAT1) transduces signals from cytokines and growth factors, particularly… (More)
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2013
2013
Wedelolactone is a major coumarin of Eclipta prostrata, which is used for preventing liver damage. However the effects of… (More)
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2012
2012
G protein-coupled receptor-35 (GPR35) has been shown to be a target of the asthma drugs cromolyn disodium and nedocromil sodium… (More)
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2012
2012
Emerging studies indicate that metabolism of arachidonic acid through the 5-lipoxygenase (5-Lox) pathway plays a… (More)
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2011
2011
The naturally occurring coumestan wedelolactone has been previously shown to reduce growth of various cancer cells. So far, the… (More)
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2007
2007
Previous reports have shown that cells infected with promastigotes of some Leishmania species are resistant to the induction of… (More)
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Highly Cited
2004
Highly Cited
2004
AbstractCaspase-11 is a key regulator of proinflammatory cytokine IL-1β maturation and pathological apoptosis. Caspase-11 is not… (More)
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2003
2003
The total synthesis of wedelolactone, a naturally occurring direct inhibitor of IKK complex that can suppress LPS-induced caspase… (More)
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1988
1988
For the study of structure-activity relationships, the antihepatotoxic wedelolactone (7-methoxy-5,11,12-trihydroxy-coumestan) and… (More)
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