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voltage-gated calcium channel activity

Known as: voltage gated calcium channel activity, voltage-sensitive calcium channel, depolarization-activated voltage-gated calcium channel activity 
Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on… Expand
National Institutes of Health

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Related topics

3 relations
negative regulation of voltage-gated calcium channel activitypositive regulation of voltage-gated calcium channel activityvoltage-gated calcium channel (VGCC)

Papers overview

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Highly Cited
2003
Highly Cited
2003
Powerful antinociceptive effects of the cone snail venom-derived subtype-selective NMDA receptor antagonists conantokins G and T
Subunit non-selective N-methyl-D-aspartate (NMDA) receptor antagonists reduce injury-induced pain behavior, but generally produce… Expand
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Highly Cited
2002
Highly Cited
2002
Cdk5/p35 regulates neurotransmitter release through phosphorylation and downregulation of P/Q-type voltage-dependent calcium channel activity.
Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase with close structural homology to the mitotic Cdks… Expand
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Highly Cited
2000
Highly Cited
2000
Fresh and globular amyloid beta protein (1-42) induces rapid cellular degeneration: evidence for AbetaP channel-mediated cellular toxicity.
Amyloid beta peptides (AbetaP) deposit as plaques in vascular and parenchymal areas of Alzheimer's disease (AD) tissues and Down… Expand
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Highly Cited
1999
Highly Cited
1999
Activation of the L voltage-sensitive calcium channel by mitogen-activated protein (MAP) kinase following exposure of neuronal cells to beta-amyloid. MAP kinase mediates beta-amyloid-induced…
Neuronal degeneration in Alzheimer's disease (AD) has been variously attributed to increases in cytosolic calcium, reactive… Expand
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Highly Cited
1998
Highly Cited
1998
Muscarinic cholinergic regulation of cardiac myocyte ICa-L is absent in mice with targeted disruption of endothelial nitric oxide synthase.
Cardiac myocytes have been shown to express constitutively endothelial nitric oxide synthase (eNOS) (nitric oxide synthase 3… Expand
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Highly Cited
1997
Highly Cited
1997
Neurotrophins protect cultured cerebellar granule neurons against the early phase of cell death by a two-component mechanism.
Cerebellar granule neurons cultured with serum develop a mature neuronal phenotype, including stimulus-coupled release of… Expand
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Highly Cited
1996
Highly Cited
1996
Absence Epilepsy in Tottering Mutant Mice Is Associated with Calcium Channel Defects
Mutations at the mouse tottering (tg) locus cause a delayed-onset, recessive neurological disorder resulting in ataxia, motor… Expand
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Highly Cited
1996
Highly Cited
1996
Selective N-type neuronal voltage-sensitive calcium channel blocker, SNX-111, produces spinal antinociception in rat models of acute, persistent and neuropathic pain.
Male Sprague-Dawley rats were used to evaluate the antinociceptive properties of the selective N-type voltage-sensitive calcium… Expand
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Highly Cited
1988
Highly Cited
1988
Voltage-sensitive calcium channels in normal and transformed 3T3 fibroblasts.
Patch clamp recordings of whole-cell and single channel currents revealed the presence of two voltage-sensitive calcium channel… Expand
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Highly Cited
1984
Highly Cited
1984
Purification of the calcium antagonist receptor of the voltage-sensitive calcium channel from skeletal muscle transverse tubules.
[3H]Nitrendipine binds with high affinity to a calcium antagonist receptor preferentially localized to the transverse tubule… Expand
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