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voltage-gated calcium channel activity

Known as: voltage gated calcium channel activity, voltage-sensitive calcium channel, depolarization-activated voltage-gated calcium channel activity 
Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on… Expand
National Institutes of Health

Related topics

Related topics

3 relations
negative regulation of voltage-gated calcium channel activitypositive regulation of voltage-gated calcium channel activityvoltage-gated calcium channel (VGCC)

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Powerful antinociceptive effects of the cone snail venom-derived subtype-selective NMDA receptor antagonists conantokins G and T
&NA; Subunit non‐selective N‐methyl‐d‐aspartate (NMDA) receptor antagonists reduce injury‐induced pain behavior, but generally… Expand
Highly Cited
2002
Highly Cited
2002
Cdk5/p35 Regulates Neurotransmitter Release through Phosphorylation and Downregulation of P/Q-Type Voltage-Dependent Calcium Channel Activity
Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase with close structural homology to the mitotic Cdks… Expand
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Highly Cited
1999
Highly Cited
1999
Activation of the L voltage-sensitive calcium channel by mitogen-activated protein (MAP) kinase following exposure of neuronal cells to beta-amyloid. MAP kinase mediates beta-amyloid-induced…
Neuronal degeneration in Alzheimer's disease (AD) has been variously attributed to increases in cytosolic calcium, reactive… Expand
Highly Cited
1998
Highly Cited
1998
Muscarinic cholinergic regulation of cardiac myocyte ICa-L is absent in mice with targeted disruption of endothelial nitric oxide synthase.
Cardiac myocytes have been shown to express constitutively endothelial nitric oxide synthase (eNOS) (nitric oxide synthase 3… Expand
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Highly Cited
1996
Highly Cited
1996
Absence Epilepsy in Tottering Mutant Mice Is Associated with Calcium Channel Defects
Mutations at the mouse tottering (tg) locus cause a delayed-onset, recessive neurological disorder resulting in ataxia, motor… Expand
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Highly Cited
1996
Highly Cited
1996
Selective N-type neuronal voltage-sensitive calcium channel blocker, SNX-111, produces spinal antinociception in rat models of acute, persistent and neuropathic pain.
Male Sprague-Dawley rats were used to evaluate the antinociceptive properties of the selective N-type voltage-sensitive calcium… Expand
Highly Cited
1994
Highly Cited
1994
L-type voltage-sensitive calcium channel activation stimulates gene expression by a serum response factor-dependent pathway.
A mechanism by which calcium-induced signals are transduced to the nucleus to activate transcription of the c-fos proto-oncogene… Expand
Highly Cited
1988
Highly Cited
1988
Voltage-sensitive calcium channels in normal and transformed 3T3 fibroblasts.
Patch clamp recordings of whole-cell and single channel currents revealed the presence of two voltage-sensitive calcium channel… Expand
Highly Cited
1985
Highly Cited
1985
Phosphorylation of the calcium antagonist receptor of the voltage-sensitive calcium channel by cAMP-dependent protein kinase.
Physiological studies indicate that voltage-sensitive calcium channels are regulated by cAMP and protein phosphorylation. The… Expand
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Highly Cited
1984
Highly Cited
1984
Purification of the calcium antagonist receptor of the voltage-sensitive calcium channel from skeletal muscle transverse tubules.
[3H]Nitrendipine binds with high affinity to a calcium antagonist receptor preferentially localized to the transverse tubule… Expand
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