vinorelbine

Known as: Vinorelbin, Dihydroxydeoxynorvinkaleukoblastine, C'-Norvincaleukoblastine, 3',4'-didehydro-4'-deoxy- 
A semisynthetic vinca alkaloid. Vinorelbine binds to tubulin and prevents formation of the mitotic spindle, resulting in the arrest of tumor cell… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
PURPOSE Docetaxel has not been compared with vinorelbine as adjuvant treatment of early breast cancer. Efficacy and long-term… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND The Lung Cancer Cetuximab Study is an open-label, randomized phase II pilot study of cisplatin and vinorelbine… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Whether adjuvant chemotherapy improves survival of patients with non-small-cell lung cancer (NSCLC) is not known. We… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND To compare the efficacy and toxicity of three platinum-based combination regimens against cisplatin plus irinotecan… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND We undertook to determine whether adjuvant vinorelbine plus cisplatin prolongs overall survival among patients with… (More)
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Highly Cited
2003
Highly Cited
2003
PURPOSE To investigate whether docetaxel plus platinum regimens improve survival and affect quality of life (QoL) in advanced non… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE This randomized trial was designed to determine whether paclitaxel plus carboplatin (PC) offered a survival advantage… (More)
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Highly Cited
2000
Highly Cited
2000
PURPOSE To confirm the promising phase II results of docetaxel monotherapy, this phase III trial was conducted of chemotherapy… (More)
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Highly Cited
1999
Highly Cited
1999
  • Journal of the National Cancer Institute
  • 1999
BACKGROUND Vinorelbine, a semisynthetic vinca alkaloid, represents a well-tolerated treatment for elderly patients with advanced… (More)
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Highly Cited
1994
Highly Cited
1994
PURPOSE We designed a prospective randomized trial to compare vinorelbine and cisplatin (NVB-P) with vindesine and cisplatin (VDS… (More)
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