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vinorelbine

Known as: Vinorelbin, Dihydroxydeoxynorvinkaleukoblastine, C'-Norvincaleukoblastine, 3',4'-didehydro-4'-deoxy- 
A semisynthetic vinca alkaloid. Vinorelbine binds to tubulin and prevents formation of the mitotic spindle, resulting in the arrest of tumor cell… 
National Institutes of Health

Related topics

Related topics

23 relations

Broader (3)

Antineoplastic Agents, PhytogenicVinblastineanhydrovinblastine
Drug AllergyHodgkin DiseaseMammary NeoplasmsMicrotubule Process

Narrower (3)

KW 2307NavelbineVinorelbine tartrate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Anthracycline- and/or taxane-resistant breast cancer: results of a literature review to determine the clinical challenges and current treatment trends.
Highly Cited
2005
Highly Cited
2005
Lateral pedicle control during laparoscopic radical prostatectomy: refined technique.
Review
2004
Review
2004
Chemotherapy for malignant pleural mesothelioma: past results and recent developments.
Highly Cited
2002
Highly Cited
2002
Phase II trial of weekly vinorelbine and trastuzumab as first-line therapy in patients with HER2(+) metastatic breast cancer.
PURPOSE Human epidermal growth factor receptor 2 (HER2) overexpression is associated with a more aggressive form of breast cancer… 
Review
2002
Review
2002
Intralesional vinblastine vs. 3% sodium tetradecyl sulfate for the treatment of oral Kaposi's sarcoma. A double blind, randomized clinical trial.
Highly Cited
1998
Highly Cited
1998
First‐line treatment of advanced nonsmall cell lung carcinoma with docetaxel and vinorelbine
Docetaxel and vinorelbine are active agents in the treatment of nonsmall cell lung carcinoma (NSCLC). The efficacy and toxicity… 
Highly Cited
1995
Highly Cited
1995
Phase II trial of weekly i.v. vinorelbine as a single agent in first-line advanced breast cancer chemotherapy. The Latin-American experience.
This study investigated the therapeutic effect of single-agent i.v. weekly Navelbine (vinorelbine), a semisynthetic vinca… 
Highly Cited
1991
Highly Cited
1991
Invasion of the neurovascular bundle by prostate cancer: evaluation with MR imaging.
Preservation of the neurovascular bundle (NVB) and potency without compromising tumor control are current objectives of radical… 
Highly Cited
1989
Highly Cited
1989
Efficacy of Navelbine (NVB) in non-small cell lung cancer (NSCLC).
Highly Cited
1985
Highly Cited
1985
Phase I pharmacologic study of a new Vinca alkaloid: navelbine.
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