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Vinblastine

Known as: VBL, Vinblastin, VLB 
A natural alkaloid isolated from the plant Vinca rosea Linn. Vinblastine binds to tubulin and inhibits microtubule formation, resulting in disruption… 
National Institutes of Health

Related topics

Related topics

47 relations

Narrower (20)

16-demethoxyvindoline4-desacetylvinblastine hydrazideCarbo-MVE protocolDMV protocol

Broader (1)

Antineoplastic Agents, Phytogenic
COPP-ABV RegimenCommunicable DiseasesDoxorubicin/Methotrexate/VinblastineMVAC Regimen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1986
Highly Cited
1986
Chloroquine enhancement of anticancer drug cytotoxicity in multiple drug resistant human leukemic cells.
Highly Cited
1985
Highly Cited
1985
Phase I pharmacologic study of a new Vinca alkaloid: navelbine.
Highly Cited
1981
Highly Cited
1981
Effects of motility inhibitors during sea urchin fertilization: microfilament inhibitors prevent sperm incorporation and restructuring of fertilized egg cortex, whereas microtubule inhibitors prevent…
Highly Cited
1979
Highly Cited
1979
Multiple sites for the initiation of microtubule assembly in mammalian cells
Highly Cited
1978
Highly Cited
1978
Characterization of the intermediate (10 nm) filaments of cultured cells using an autoimmune rabbit antiserum
Highly Cited
1975
Highly Cited
1975
Melatonin effects on brain. Interaction with microtubule protein, inhibition of fast axoplasmic flow and induction of crystaloid and tubular formations in the hypothalamus
Highly Cited
1973
Highly Cited
1973
Mitotic arrest by melatonin.
Highly Cited
1973
Highly Cited
1973
Soluble microtubule proteins of the sea urchin embryo: partial characterization of the proteins and behavior of the pool in early development.
Highly Cited
1972
Highly Cited
1972
F1-histone modification at metaphase in Chinese hamster cells.
Highly Cited
1970
Highly Cited
1970
STRUCTURE OF MICROTUBULAR CRYSTALS INDUCED BY VINBLASTINE IN VITRO
The treatment of any of a wide variety of cells with vincristine or vinblastine results in the dissolution of cytoplasmic… 
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