anhydrovinblastine

Known as: AVLB 
A semisynthetic derivative of the vinca alkaloid vinblastine, with potential antineoplastic activity. Like vinblastine, anhydrovinblastine targets… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2016
012319842016

Papers overview

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2008
2008
A series of novel hybrid compounds obtained by the attachment of anhydrovinblastine, vinorelbine, and vindoline to thiocolchicine… (More)
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2008
2008
Catharanthus roseus produces low levels of two dimeric terpenoid indole alkaloids, vinblastine and vincristine, which are widely… (More)
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2007
2007
A high performance liquid chromatographic (HPLC) method with gradient elution was developed for the simultaneous determination of… (More)
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2007
2007
A series of 3-demethoxycarbonyl-3-carbamate methyl anhydrovinblastine derivatives (compounds 8b-32b) were designed, synthesized… (More)
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2003
2003
We have characterized a basic peroxidase with α-3′,4′-anhydrovinblastine (AVLB) synthase activity, which was purified from… (More)
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2002
2002
[reaction: see text] The Cp(2)TiCl-mediated deoxygenation of leurosine (1) afforded anhydrovinblastine (4) in good yield… (More)
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2002
2002
Straightforward access to anhydrovinblastine starting from the parent alkaloid leurosine is reported. The key deoxygenation step… (More)
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1998
1998
An H2O2-dependent enzyme capable of coupling catharanthine and vindoline into alpha-3',4'-anhydrovinblastine (AVLB) was purified… (More)
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1994
1994
BACKGROUND This study evaluated the therapeutic effect of the weekly administration of vinorelbine (5'-nor-anhydrovinblastine), a… (More)
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1984
1984
We have found that navelbine, a new semi-synthetic Vinca alkaloid analogue, is as active as vincristine on implanted murine… (More)
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