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vinflunine

Known as: 4'-Deoxy-20',20'-difluoro-C'-norvincaleukoblastine 
A bi-fluorinated derivative of the semi-synthetic vinca alkaloid vinorelbine with antitubulin, antineoplastic, and antiangiogenic activities… 
National Institutes of Health

Related topics

Related topics

6 relations

Narrower (1)

Javlor
Microtubule ProcessNCIt Antineoplastic Agent TerminologyVinflunine Ditartrateanalogs & derivatives

Broader (1)

Vinblastine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Recent advances in genitourinary tumors: A review focused on biology and systemic treatment.
Review
2012
Review
2012
Eribulin mesylate, a novel microtubule inhibitor in the treatment of breast cancer.
2011
2011
Synthesis and study of a molecularly imprinted polymer for the specific extraction of indole alkaloids from Catharanthus roseus extracts.
Review
2011
Review
2011
Vinflunine: drug safety evaluation of this novel synthetic vinca alkaloid
Introduction: Vinca alkaloid agents have been widely used in several different types of malignancies. However, cancer cells… 
Review
2011
Review
2011
Therapeutic management of breast cancer in the elderly
Introduction: Over the last few decades, the population of developed countries has aged. Breast cancer is the most common cancer… 
2008
2008
Antiangiogenic vinflunine affects EB1 localization and microtubule targeting to adhesion sites
The motile behavior of endothelial cells is a crucial event for neoangiogenesis. We previously showed that noncytotoxic… 
2008
2008
Vinflunine in the treatment of bladder cancer
Vinflunine (VFL) is a third-generation bifluorinated semi-synthetic vinca alkaloid obtained by superacidic chemistry from its… 
2007
2007
Vinflunine, a novel microtubule inhibitor, suppresses calmodulin interaction with the microtubule-associated protein STOP.
Vinca alkaloids vinblastine and vincristine and some of their derivatives such as vinorelbine are widely used in therapy of… 
Highly Cited
2006
Highly Cited
2006
Antiangiogenic concentrations of vinflunine increase the interphase microtubule dynamics and decrease the motility of endothelial cells.
Angiogenesis is a key event in tumor progression and metastasis. This complex process, which constitutes a potent target for… 
2002
2002
Optimization of the separation of Vinca alkaloids by nonaqueous capillary electrophoresis.
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